Dynamically modified, biospecific optical fiber sensor for riboflavin binding protein based on hydrophobically associated 3-octylriboflavin.
Dynamically modified, biospecific optical fiber sensor for riboflavin binding protein based on hydrophobically associated 3-octylriboflavin.
复制标题
基于疏水相关 3-辛基核黄素的动态修饰、生物特异性光纤传感器，用于核黄素结合蛋白。
DOI：
10.1021/ac00039a003
复制
发表时间：
1992
影响因子：
7.4
通讯作者：
Bobbitt,DR
中科院分区：
文献类型：
--
作者：
Ogasawara,FK;Wang,Y;Bobbitt,DR
化学分析领域的最新发展已经指向化学传感器的小型化。这一努力的动力在于希望生产能够检测指示疾病状态的各种化学和生物化学物质的体内传感器。在不干扰所研究体系的情况下充分探测这些体系是当今化学分析领域的巨大挑战之一。一个令人兴奋的发展是使用光纤来传输和收集来自特定区域的光，其中光纤远端的光相互作用可以用来获得关于光纤尖端发生的化学事件的知识。1光纤，由于其直径小，可用于生产非常小的光学探头（optrodes），并且由于光可以在光纤中长距离传播而没有明显的损失，因此它们可以有效地用于远程监控情况。作为一个例子，已经描述了一种光纤传感器，其适合于通过溶液折射率对传输特性的影响来监测葡萄糖水平
Recent developments in the fieldof chemical analysis have been directed toward the miniaturization of chemical sensors. The impetus for this effort lies in the desire to produce in vivo sensors capable of detecting a variety of chemicaland biochemical materials indicativeof the diseased state. To probe these systems adequately without perturbing the system under study is one of the great challenges in the field of chemical analysis today. One exciting development has been the use of optical fibers to deliver and collect light from specific regions wherethe light interactions at the distal end of the fiber can be used to gain knowledge about the chemical events occurring at the fiber tip.* 1 Optical fibers, because of their small diameters, can be used to produce extremely small optical probes (optrodes), and because light can be propagated in optical fibers over long distances without appreciable loss, they can be used effectively in remote monitoring situations. As an example, an optical fiber sensor has been described which is suitable for monitoring glucose levels via the effect of the solution refractive index on the transmission properties