Solubility of Benzimidazoles in Alcohols
Solubility of Benzimidazoles in Alcohols
复制标题
DOI：
10.1021/je020228x
复制
发表时间：
2003-04
影响因子：
--
通讯作者：
U. D. and;Ewa Bogel-Łukasik
中科院分区：
文献类型：
--
作者：
U. D. and;Ewa Bogel-Łukasik
用动态法测定了苯并咪唑（苯并咪唑和2-甲基苯并咪唑）与醇（1-丙醇、1-丁醇、2-丁醇、2-甲基-2-丙醇、1-己醇）的10种二元混合物在270 ~ 445 K的固液平衡。通过差示扫描量热法（DSC）测定熔点、熔化焓和在熔化温度下的热容变化。苯并咪唑在醇（C3-C6）中的溶解度高于在水和1-辛醇中的溶解度，并且通常随着醇的烷基链长度的增加而降低。1-醇的分子间溶质-溶剂相互作用高于仲醇或叔醇。2-甲基苯并咪唑在醇（C3−C6）中的溶解度高于苯并咪唑。溶解度的实验结果通过Wilson、UNIQUAC ASM和NRTL 1方程利用来自SLE结果的参数进行关联。一级相变的存在……
The solid−liquid equilibrium (SLE) has been measured from 270 K to 445 K for 10 binary mixtures of benzimidazoles (benzimidazole and 2-methylbenzimidazole) with alcohols (1-propanol, 1-butanol, 2-butanol, 2-methyl-2-propanol, 1-hexanol) using a dynamic method. The melting point, enthalpy of fusion, and heat capacity change at the melting temperature were determined by differential scanning calorimetry (DSC). The solubility of benzimidazoles in alcohols (C3−C6) is higher than in water and in 1-octanol and generally decreases with an increase of the alkyl chain length of the alcohol. The intermolecular solute−solvent interaction is higher for the 1-alcohol than for the secondary or tertiary alcohol. The solubility of 2-methylbenzimidazole in alcohols (C3−C6) is higher than that of benzimidazole. Experimental results of solubility were correlated by means of the Wilson, UNIQUAC ASM, and NRTL 1 equations utilizing parameters derived from SLE results. The existence of a solid−solid first-order phase transition...