Daily home opioid use in adults with sickle cell disease: The PiSCES project.
Daily home opioid use in adults with sickle cell disease: The PiSCES project.
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DOI：
10.5055/jom.2015.0273
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发表时间：
2015-05-01
影响因子：
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通讯作者：
Roseff, Susan D
中科院分区：
文献类型：
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作者：
Smith, Wally R;McClish, Donna K;Roseff, Susan D
BACKGROUND: Although opioid prescribing in sickle cell disease (SCD) can be controversial, little is published about patterns of opioid use.OBJECTIVE: To report on home opioid use among adults with SCD.DESIGN: Cohort study.PARTICIPANTS: Adults with SCD (n=219) who completed daily pain diaries for up to 6 months and had at least one home pain day.MAIN MEASURES: Use of long-acting or short-acting opioids, other analgesics, or adjuvants; the proportion of home days, home pain days, and home crisis days with opioid use; these two outcomes according to patient characteristics.KEY RESULTS: Patients used opioids on 12,311 (78 percent) of 15,778 home pain days. Eighty-five patients (38.8 percent) used long-acting opioids with or without short-acting opioids and 103 (47.0 percent) used only short-acting opioids. Twenty-one (9.6 percent) patients used only non-opioid analgesics and 10 (4.6 percent) used no analgesics. Both pain intensity and pain frequency were higher among opioid users (analysis of variance [ANOVA], p
