Fabrication of diverse microcapsule arrays of high density and good stability.
Fabrication of diverse microcapsule arrays of high density and good stability.
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DOI：
10.1002/marc.200900901
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发表时间：
2010-06
影响因子：
4.6
通讯作者：
Jiegeng Yang;Changyou Gao
中科院分区：
文献类型：
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作者：
Jiegeng Yang;Changyou Gao
微胶囊阵列由于其在传感技术中的潜在应用而引起了广泛的兴趣。本文报道了一种通过共价键连接制备不同微胶囊阵列的方法。通过使用聚（烯丙基胺盐酸盐）（PAH）图案化的模板，这是通过微接触印刷创建的自组装微胶囊的指导。以PAH为最外层的微胶囊用戊二醛处理，然后共价固定在PAH区域上，得到有序的微胶囊阵列。该阵列具有高密度的胶囊，并且可以通过调节PAH图案的面积来很好地控制图案中的聚集体数量。如果PAH区域的直径小于微胶囊的直径，则可以获得单个微胶囊阵列。这些共价组装的阵列可以通过在高离子强度和极端pH值的溶液中连续孵育而存活。这种良好的稳定性确保了进一步的处理，例如化学反应和功能物质的负载。
Microcapsule arrays attract a lot of interest due to their potential applications in sensing technology. A strategy for fabricating diverse microcapsule arrays through covalent linking is reported here. The self-assembly of microcapsules was directed by using a poly(allylamine hydrochloride) (PAH)-patterned template, which was created via microcontact printing. The microcapsules with PAH as the outermost layer were treated with glutaraldehyde and then covalently immobilized on the PAH regions, resulting in ordered microcapsule arrays. The arrays had a high density of capsules and the aggregate number in a pattern could be well controlled by adjusting the area of the PAH pattern. A single microcapsule array could be obtained if the diameter of the PAH region was smaller than that of the microcapsules. These covalently assembled arrays could survive through successive incubation in solutions of high ionic strength and extreme pHs. Such good stability ensures further treatments, such as chemical reactions and loading of functional substances.