Ventilator-associated events: prevalence and mortality in Japan
Ventilator-associated events: prevalence and mortality in Japan
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DOI：
10.21037/jtd.2018.12.40
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发表时间：
2018-12-01
影响因子：
2.5
通讯作者：
Shime, Nobuaki
中科院分区：
文献类型：
--
作者：
Nakahashi, Susumu;Imai, Hiroshi;Shime, Nobuaki
背景：2013年，美国疾病控制和预防中心(CDC)发布了呼吸机相关事件(VAEs)的概念，将其作为重症监护病房(ICU)的质量指标。美国和其他西方国家已经进行了多项研究，以评估其实用性。然而，关于非西方国家的虚拟企业的信息很少。这项初步研究的目的是阐明VAEs在日本的发病率和相关死亡率，作为确定其实用性的第一步。方法：我们使用VAEs监测算法对患者的病历进行了多中心的回顾。我们分析了785名在日本7家城市医院的重症监护室接受机械呼吸机(MV)治疗2天的患者。结果：共检出49例VAEs，发生率为5.7%，平均每1000 mVd有6.4例VAEs。发生血管内静脉栓塞者的死亡率为42.9%，显著高于队列中其他患者的死亡率(15.4%，P
Background: In 2013, the Centers for Disease Control and Prevention (CDC) issued the concept of the ventilator-associated events (VAEs) as a quality indicator (QI) in the intensive care unit (ICU). A number of studies have been conducted in the United States and other Western countries to evaluate its practicality. However, information on VAEs in non-Western countries is scarce. The purpose of this preliminary study was to illuminate the incidence and associated mortality rate of VAEs in Japan, as a first step in the effort to determine its practicality.Methods: We conducted a multi-center, retrospective review of patient medical record using VAEs surveillance algorithm. We analyzed 785 patients with >= 2 days of mechanical ventilator (MV), admitted to the ICU at seven urban hospital in Japan. The prevalence of VAEs, including its three subtypes, and in-ICU mortality were researched.Results: Forty-nine VAEs were identified, affecting 5.7% of patients requiring MV for >= 2 days and 6.4 per 1,000 MV days. Mortality in those who developed VAEs was 42.9%, significantly higher than the rest of the cohort (vs. 15.4%, P