Open randomised trial of intermittent very low energy diet together with nicotine gum for stopping smoking in women who gained weight in previous attempts to quit
Open randomised trial of intermittent very low energy diet together with nicotine gum for stopping smoking in women who gained weight in previous attempts to quit
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DOI：
10.1136/bmj.319.7208.490
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发表时间：
1999-08-21
影响因子：
--
通讯作者：
Westin, Å
中科院分区：
文献类型：
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作者：
Danielsson, T;Rössner, S;Westin, Å
目的确定是否尝试防止体重增加将增加戒烟的成功率。设计16周，开放，随机研究，随访1年，设置肥胖单位。受试者287名女性吸烟者谁曾戒烟，但由于体重问题再次开始。干预结合标准的戒烟计划与尼古丁口香糖和行为体重控制计划，包括一个非常低的能量饮食.对照组采用相同的方案治疗，但没有diet.Main结果测量持续戒烟。结果16周后，饮食组68/137（50%）女性戒烟，对照组53/150（35%）（P = 0.01）。在这些妇女中，饮食组体重平均下降2.1（95%置信区间2.9 - 1.3）kg，而对照组体重平均增加1.6（0.9 - 2.3）kg（P < 0.001）。1年后，饮食组和对照组的成功率分别为38/137（28%）和24/150（16%）（P < 0.05），但体重增加差异无统计学意义。
Objective To determine whether attempts to prevent weight gain will increase success rates for stopping smoking.Design 16 week, open, randomised study with I year follow up,Setting Obesity unit.Subjects 287 female smokers who had quit smoking before but started again because of weight concerns.Intervention Combination of a standard smoking cessation programme with nicotine gum and a behavioural weight control programme including a very low energy diet. A control group was treated with the identical programme but without the diet.Main outcome measure Sustained cessation of smoking.Results After 16 weeks, 68/137 (50%) women had stopped smoking in the diet group versus 53/150 (35%) in the control group (P = 0.01). Among these women, weight fell by mean 2.1 (95% confidence interval 2.9 to 1.3) kg in the diet group but increased by 1.6 (0.9 to 2.3) kg in die control group (P < 0.001). After 1 year the success rates in the diet and control groups were 38/137 (28%) and 24/150 (16%) respectively (P < 0.05), but: there tvas no statistical difference in weight gain.Conclusions Combining the smoking cessation programme with an intervention to control weight helped women to stop smoking and control weight.