Multiple-locus departures from panmictic equilibrium within and between village gene pools of Amerindian tribes at different stages of agglomeration.
Multiple-locus departures from panmictic equilibrium within and between village gene pools of Amerindian tribes at different stages of agglomeration.
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处于不同集聚阶段的美洲印第安部落村庄基因库内部和之间的多位点偏离了恐慌平衡。
DOI：
10.1093/genetics/104.1.133
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发表时间：
1983
期刊：
影响因子：
3.3
通讯作者：
W. Liu
中科院分区：
文献类型：
--
作者：
P. Smouse;J. Neel;W. Liu
从多轨迹哈代-温伯格平衡的偏离的比较分析，提出了一套四个部落的印第安人群体（Yanomama，Makiritare，Wapishana和Ticuna）从低地的南美洲。这些部落跨越了一系列的聚集和文化适应，从最传统的，挥霍的园艺家到边境城镇居民。传统园艺家典型的小群体社会组织导致了部落panmixia的实质性偏离，表现为多位点基因型在村庄内和村庄之间的分布。在村庄内，偏离单位点Hardy-Weinberg平衡是小的和不显着的，但偏离配子平衡（独立的基因座）是实质性的，即使是我们用来描述这些人群的非连锁基因座。各村庄的单点同质性偏离也很大。在这种情况下，文化适应的增加通常伴随着凝聚力的增加。随着聚集的增加，与多位点泛混合的偏离减少，这是一个非常迅速的过程。我们讨论了进化的平衡转移理论和间断的进化速率，根据小群体的社会组织，必须在大多数人类进化中获得。
A comparative analysis of departures from multiple-locus Hardy-Weinberg equilibrium is presented for a set of four tribal Indian groups (the Yanomama, Makiritare, Wapishana and Ticuna) from the lowlands of South America. These tribes span a range of agglomeration and acculturation from the most traditional, swidden horticulturalists to frontier townspeople. The small-group social organization typical of traditional horticulturalists leads to substantial departures from tribal panmixia, as manifested by the distribution of multiple-locus genotypes both within and between villages. Within villages, the departures from single-locus Hardy-Weinberg equilibrium are small and nonsignificant, but the departures from gametic equilibrium (independence of loci) are substantial, even for the unlinked loci we have used to characterize these populations. The departures from single-locus homogeneity across villages are also substantial. One of the normal concomitants of increasing acculturation in this setting is an increase in agglomeration. As agglomeration increases, the departures from multiple-locus panmixia decrease, a process that can be very rapid. We discuss both the shifting balance theory of evolution and punctuated evolutionary rates in light of the small group social organization that must have obtained throughout most of human evolution.