Two-piece customized mold technique for high-dose-rate brachytherapy on cancers of the buccal mucosa and lip
Two-piece customized mold technique for high-dose-rate brachytherapy on cancers of the buccal mucosa and lip
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DOI：
10.1016/j.tripleo.2011.06.038
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发表时间：
2012-01-01
影响因子：
2.9
通讯作者：
Asaumi, Jun-Ichi
中科院分区：
文献类型：
--
作者：
Matsuzaki, Hidenobu;Takemoto, Mitsuhiro;Asaumi, Jun-Ichi
目标。使用定制模具的高剂量率(HDR)近距离放射治疗是口腔癌的微创治疗；然而，由于其解剖形式，这种技术很难用于涉及唇连合口的颊和唇癌。本研究的目的是介绍一种改进的定制模具，它由两个部件组成，可以将模具固定到这些部位。研究设计。对5例口腔癌和1例唇癌患者外照射后采用该技术进行治疗。1例颈部转移瘤患者在接受HDR近距离放射治疗前同时行颈淋巴清扫术和肿瘤部分切除。随访期结束时，5例无肿瘤复发，1例局部复发。对于口腔癌和唇癌患者来说，我们的技术是一种可行的治疗选择，这些患者的治疗方式受到年龄、表现状况和其他因素的限制。(《口腔外科》《口腔医学》《口腔病理》《口腔放射学》2012；113：118-125)
Objective. High-dose-rate (HDR) brachytherapy using a customized mold is a minimally invasive treatment for oral cancer; however, it is difficult to use this technique for buccal and lip cancers involving the commissura labiorum, owing to its anatomic form. The purpose of this study was to introduce an improved customized mold consisting of 2 pieces to allow the fixation of molds to these sites.Study design. Five patients with buccal carcinoma and 1 patient with lip carcinoma were treated with this technique after external beam radiotherapy. One patient with neck metastasis underwent both neck dissection and partial tumor resection before HDR brachytherapy.Results. At the end of the follow-up period, 5 patients had no tumor recurrence, and 1 patient had suffered local recurrence.Conclusions. Our technique is a viable therapeutic option for patients with buccal and lip carcinomas for whom the therapeutic modalities are limited by age, performance status, and other factors. (Oral Surg Oral Med Oral Pathol Oral Radiol 2012;113:118-125)