Probe microrheology without particle tracking by differential dynamic microscopy
Probe microrheology without particle tracking by differential dynamic microscopy
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DOI：
10.1007/s00397-017-1047-7
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发表时间：
2017-11-01
期刊：
影响因子：
2.3
通讯作者：
Helgeson, Matthew E.
中科院分区：
文献类型：
--
作者：
Bayles, Alexandra V.;Squires, Todd M.;Helgeson, Matthew E.
我们提出了一种新的方法进行被动探针显微流变学。使用一个简单的理论框架，我们展示了如何探针的均方位移可以通过分析通过微分动态显微镜（DDM）的光学显微镜视频中的强度波动提取。将该方法应用于牛顿流体和粘弹性流体中的光学稀释探针，定量地再现了从多粒子跟踪（MPT）中提取的均方位移，并暴露了DDM的相对优势和劣势。此外，DDM可用于测量MPT失效的光学致密流体中的均方粘度，表明DDM可以扩展微观流变学实验的范围，同时规避MPT的许多缺点。
We present a new method for performing passive probe microrheology. Using a simple theoretical framework, we show how probes' mean-squared displacements can be extracted by analyzing intensity fluctuations in optical microscopy videos via differential dynamic microscopy (DDM). Applying the method to optically dilute probes in Newtonian and viscoelastic fluids quantitatively reproduces mean-squared displacements extracted from multiple particle tracking (MPT), and exposes the relative strengths and weakness of DDM. Furthermore, DDM can be used to measure the mean-squared displcement in optically dense fluids where MPT fails, demonstrating that DDM can extend the range of microrheology experiments while circumventing many of the drawbacks of MPT.