Atomic force microscopy of biomaterials surfaces and interfaces
Atomic force microscopy of biomaterials surfaces and interfaces
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DOI：
10.1016/s0039-6028(01)01296-1
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发表时间：
2001-10-01
期刊：
影响因子：
1.9
通讯作者：
Jandt, KD
中科院分区：
文献类型：
--
作者：
Jandt, KD
原子力显微镜（AFM）在生物材料科学和工程应用中的使用在过去几年中迅速增加。除了作为一种测量表面形貌的工具之外，AFM还为处理生物材料表面和界面的结构、性质、动力学和操作的各种生物材料研究领域做出了重大贡献。本文批判性地回顾了方法学的方法，并介绍了这项研究的各个方面。选定的例子包括微观和纳米结构和生物材料表面的性质，在生物材料-生物分子界面的分子水平的相互作用，生物材料和矿化组织之间的界面，以及矿化组织研究的进展。在这些领域中，原子力显微镜被证明是一个有用的和通用的工具，研究微观和纳米结构，探测机械性能或调查动态过程中的生物材料表面和界面。(C)2001 Elsevier Science B. V.保留所有权利。
The use of atomic force microscopy (AFM) in biomaterials science and engineering applications has increased rapidly over the last few years. Beyond being merely a tool for measuring surface topography, AFM has made significant contributions to various biomaterials research areas dealing with the structure, properties, dynamics and manipulation of biomaterials surfaces and interfaces. This paper critically reviews methodological approaches and presents aspects of this research. Selected examples presented include micro and nanostructure and properties of biomaterials surfaces, molecular level interactions at biomaterial-biomolecule interfaces, interfaces between biomaterials and mineralised tissues as well as advances of mineralised tissue research. In these areas, AFM is shown to be a useful and versatile tool to study micro and nanostructure, to probe mechanical properties or to investigate dynamic process at biomaterials surfaces and interfaces. (C) 2001 Elsevier Science B.V. All rights reserved.