The Theory of the Study of Transfers within a Multi‐Compartment System Using Isotopic Tracers

The Theory of the Study of Transfers within a Multi‐Compartment System Using Isotopic Tracers
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使用同位素示踪剂研究多室系统内转移的理论

DOI:
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发表时间:
1948
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影响因子:
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通讯作者:
C. Sheppard
C. Sheppard
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文献类型:
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作者:
C. Sheppard

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表达式推导出一个系统的n个隔间,其中的量的物质S已从任何一个隔间移动到任何其他可以确定在一个单一的实验从测量的量的n个标记的物种在各个隔间。它表明,n个单独的物种的S必须是均匀混合和行为相同,但必须由观察者区分。应用方程的研究,使用多种同位素示踪剂进行了描述,并详细分析了特殊情况下的两室系统。
Expressions are derived for a system of n compartments whereby the amount of a substance S which has moved from any one compartment to any other can be determined in a single experiment from measurements of the amounts of n tagged species in the individual compartments. It is shown that n individual species of S are required which must be uniformly mixed and behave identically but must be distinguishable by the observer. The application of the equations to studies using multiple isotopic tracers is described, and the special case of a two compartment system is analyzed in detail.