POSSIBLE ACCELERATION OF AGE EFFECTS ON COGNITION FOLLOWING MENOPAUSE

POSSIBLE ACCELERATION OF AGE EFFECTS ON COGNITION FOLLOWING MENOPAUSE
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DOI:
10.1016/0022-3956(95)00005-p
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发表时间:
1995-05-01
影响因子:
4.8
通讯作者:
JOE, SH
JOE, SH
中科院分区:
医学2区
文献类型:
--
作者:
HALBREICH, U;LUMLEY, LA;JOE, SH

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许多认知功能已被证明会随着年龄的增长而恶化。由于更年期作为女性生命周期中一个里程碑的重要性,我们研究了育龄女性和绝经后女性之间某些认知功能随时间的老化过程是否存在差异。这里证明,在一些认知测试中,包括驾驶模拟、反应时间和一些视觉空间测试,绝经后功能的恶化显着加速。有人认为,这种加速可能与性腺激素或其他生殖相关因素的缺乏有关,这些因素可能对女性某些认知功能的年龄相关退化起到保护作用。
Many cognitive functions have been shown to deteriorate with age. Because of the importance of the menopause as a milestone in the life cycles of women, we examined whether the aging-over-time process in some cognitive functions differs between women of reproductive age and postmenopausal women. It is demonstrated here that in some cognitive tests, including driving simulation, reaction time and some visuospatial tests, there is a significant acceleration in deterioration of functioning following menopause. It is suggested that this acceleration might be associated with the lack of gonadal hormones or other reproduction-related factors which may play a protective role against age-related deterioration in some cognitive functions in women.