Pretreatment patient factors predicting attrition from a multicenter randomized controlled treatment study for panic disorder

Pretreatment patient factors predicting attrition from a multicenter randomized controlled treatment study for panic disorder
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DOI:
10.1016/s0010-440x(98)90043-8
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发表时间:
1998-11-01
影响因子:
7.3
通讯作者:
Woods, SW
Woods, SW
中科院分区:
医学2区
文献类型:
--
作者:
Grilo, CM;Money, R;Woods, SW

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本研究从惊恐障碍的临床试验中检测了与磨耗相关的治疗前因素。研究组由162名开始接受Ii-visit治疗的患者组成。6个领域(人口统计学,惊恐障碍的严重程度,精神共病,疾病/治疗归因,应对方式和人格风格)的52个变量被用来预测磨损。122名患者完成治疗,40名患者退出治疗。最后的多元回归分析表明,以下两个变量是独立相关的磨损:较低的家庭收入和消极的治疗态度,归因于生活压力和更大的年龄恐慌症与磨损的趋势水平。初步分析表明,此外,磨损和较低的教育,较短的长度之前的治疗,更高的焦虑敏感性,较低的广场恐惧回避,并寻求社会支持的应对方式,最佳预测分析没有证实之间的关联。精神病共病和人格风格与自然减员无关。这些研究结果对未来的研究和临床实践的影响进行了讨论。版权所有(C)1998由W.B.桑德斯公司
This study examined pretreatment factors associated with attrition from a clinical trial for panic disorder. The study group consisted of 162 patients who began Ii-visit treatments. Six domains (demography, panic disorder severity, psychiatric comorbidity, illness/treatment attributions, coping styles, and personality styles) with 52 variables were used to predict attrition. One hundred twenty-two patients completed and 40 dropped out from treatment. Final multivariate regression analyses showed that the following two variables were independently associated with attrition: lower household income and negative treatment attitudes; attributing the panic disorder to life stressors and greater age were independently associated with attrition at the trend level. Preliminary analyses suggested, in addition, associations between attrition and lower education, shorter length of prior treatment, higher anxiety sensitivity, lower agoraphobic avoidance, and a coping style of seeking social support that were not confirmed by best predictor analysis. Psychiatric comorbidity and personality styles were unrelated to attrition. The implications of these findings for future research and clinical practice are discussed. Copyright (C) 1998 by W.B. Saunders Company.