Two chloroplastic viroids induce the accumulation of small RNAs associated with posttranscriptional gene silencing
Two chloroplastic viroids induce the accumulation of small RNAs associated with posttranscriptional gene silencing
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DOI：
10.1128/jvi.76.24.13094-13096.2002
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发表时间：
2002-12-01
影响因子：
5.4
通讯作者：
Hernández, C
中科院分区：
文献类型：
--
作者：
Martínez de Alba, AE;Flores, R;Hernández, C
在植物中，转录后基因沉默（PTGS）已被报道用于内源性核基因、转基因、病毒的细胞质rna，以及最近用于具有核复制和积累的类病毒。然而，线粒体或叶绿体rna的这种现象尚未被描述。我们发现在叶绿体中复制和积累的类病毒也是PTGS的靶标，这一过程可能控制类病毒的滴度。
In plants, posttranscriptional gene silencing (PTGS) has been reported for cytoplasmic RNAs from endogenous nuclear genes, transgenes, viruses, and, recently, for a viroid with nuclear replication and accumulation. However, phenomena of this kind have not been described for mitochondrial or chloroplastic RNAs. Here we show that viroids that replicate and accumulate in the chloroplast are also targets of PTGS and this process may control viroid titer.