The reliability of self-reported blood in urine and schistosomiasis as indicators of Schistosoma haematobium infection in school children: a study in Muheza District, Tanzania
The reliability of self-reported blood in urine and schistosomiasis as indicators of Schistosoma haematobium infection in school children: a study in Muheza District, Tanzania
复制标题
DOI：
10.1046/j.1365-3156.1997.d01-209.x
复制
发表时间：
1997-12-01
影响因子：
3.3
通讯作者：
Bundy, D
中科院分区：
文献类型：
--
作者：
Ansell, J;Guyatt, H;Bundy, D
对学童自我报告的尿血和血吸虫病的使用情况进行了调查，以此作为估计埃及血吸虫感染率和确定受感染者的工具。对坦桑尼亚Muheza区137所小学的25443名儿童进行了一项关于常见健康问题的一般问卷调查，包括尿血和血吸虫病的问题。计算了每所学校报告的血吸虫病患病率，并在患病率范围内选择了15所学校。对15所学校的所有儿童（n = 2370）再次由护士进行访谈，并提供尿液样本，对这些样本进行S.通过过滤分离出嗜血杆菌。在15所学校的访问报告的血吸虫病患病率与问卷调查期间报告的患病率密切相关。在采访中报告的血吸虫病的患病率与通过显微镜检查确定的感染患病率密切相关，并且在患病率从22%到93%的范围内，持续低估了后者约20%。通过访谈进行诊断的敏感性几乎与感染的流行率呈线性增加，因此，当流行率高时，更多的感染儿童报告血吸虫病。自我诊断正确的儿童比例与感染率和尿液中虫卵的平均浓度无关，平均为75%。这些研究结果表明，自我报告血吸虫病是一个有用的方法来估计感染的流行在学校，并可能被用来识别感染的个人。
The use of self-reported blood in urine and schistosomiasis by school children was investigated as a tool to estimate the prevalence of infection with Schistosoma haematobium and to identify infected individuals. A general questionnaire about common health problems, including questions about blood in urine and schistosomiasis, was administered by teachers to 25443 children in 137 primary schools in Muheza District, Tanzania. The prevalence of reported schistosomiasis was calculated for each school and used to select 15 schools across a range in prevalence. All children in the 15 schools (n = 2370) were interviewed again by a nurse and gave a urine sample which was subjected to a quantitative microscopical examination for the eggs of S. haematobium by filtration. The prevalence of reported schistosomiasis by the interview in the 15 schools correlated strongly with the prevalence reported during the questionnaire survey. The prevalence of reported schistosomiasis in the interview was strongly correlated with the prevalence of infection determined by microscopy and consistently under-estimated the latter by around 20% across a range in prevalence from 22% to 93%. The sensitivity of diagnosis by an interview increased almost linearly with the prevalence of infection, so that when the prevalence was high, more infected children reported schistosomiasis. The percentage of children who were correct in their self-diagnosis was independent of the prevalence of infection and of the mean concentration of eggs in urine, and averaged 75%. These findings suggest that self-reported schistosomiasis is a useful method to estimate the prevalence of infection in schools and might be used to identify infected individuals.