RELATIONSHIP BETWEEN RESPIRATORY NERVE AND MUSCLE-ACTIVITY AND MUSCLE FORCE OUTPUT
RELATIONSHIP BETWEEN RESPIRATORY NERVE AND MUSCLE-ACTIVITY AND MUSCLE FORCE OUTPUT
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DOI：
10.1152/jappl.1975.39.4.567
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发表时间：
1975-01-01
影响因子：
3.3
通讯作者：
ELDRIDGE, FL
中科院分区：
文献类型：
--
作者：
ELDRIDGE, FL
为探讨呼吸神经和呼吸肌电活动的最佳利用方法，在麻醉猫上记录了呼吸肌收缩时膈神经和肋间外肌（ICM）的活动以及呼吸肌收缩引起的气道压力变化。根据每0.1秒的峰值和平均吸气率以及每次呼吸的总活动对电活动进行整流、整合和处理。膈神经活动峰值频率与吸气峰压呈高度线性相关（r = 0.974）。平均膈神经频率显示出类似的高相关性（r = 0.973）。ICM峰值速率与峰值压力呈线性相关，但相关性较差（r = 0.915）。每次呼吸的总膈神经活动太依赖于吸气持续时间，不能成为令人满意的相关性（r = 0.674）。在本实验中，咬合压力是肌肉力量产生和呼吸控制系统输出的指标。它的结论是，膈活动的峰值或平均速率提供了输出变化的电指标。从理论上讲，峰值速率可能更好。
To demonstrate the most satisfactory way of using electrical activities of respiratory nerves and muscles, activities of phrenic nerve and external intercostal muscle (ICM) and the airway pressure changes generated by respiratory muscle contraction were recorded in anesthetized cats during complete airway occlusion. Electrical activities were rectified, integrated and processed in terms of peak and average inspiratory rates per 0.1 s and of total activity per breath. Peak rate of phrenic nerve activity exhibited a high linear correlation (r = 0.974) with peak inspiratory pressure. Average phrenic rate showed a similar high correlation (r = 0.973). Peak rate of external ICM was linearly related to peak pressure but the correlation was less good (r = 0.915). Total phrenic activity per breath was too dependent upon inspiratory duration to be a satisfactory correlate (r = 0.674). In this experiment occlusion pressure was an index of muscle force generation and respiratory control system output. It is concluded that peak or average rates of phrenic activity provide an electrical index of output changes. On theoretical grounds, peak rate is probably better.