NUCLEUS ACCUMBENS OF RATS AND DOPAMINERGIC MECHANISMS REGULATING LOCOMOTOR BEHAVIOR
NUCLEUS ACCUMBENS OF RATS AND DOPAMINERGIC MECHANISMS REGULATING LOCOMOTOR BEHAVIOR
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DOI：
10.1016/0304-3940(76)90064-1
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发表时间：
1976-01-01
影响因子：
2.5
通讯作者：
VANROSSUM, JM
中科院分区：
文献类型：
--
作者：
COOLS, AR;HONIG, WMM;VANROSSUM, JM
将多巴胺和(3，4-二羟基苯氨基)-2-咪唑啉(DPI)注射到局部注射麦角新碱的大鼠伏隔核内。结果表明，两种化合物均抑制麦角新碱诱导的运动活动，提示麦角新碱对某些类型的多巴胺受体有抑制作用。这些数据是根据不同类型的多巴胺受体进行讨论的。
Dopamine and (3,4-dihydroxyphenylamino)-2-imidazoline (DPI) were injected into the nucleus accumbens of rats locally pretreated with ergometrine. The results show that the ergometrine-induced locomotor activity is inhibited by both compounds suggesting that ergometrine inhibits certain types of dopamine receptors. The data were discussed in terms of distinct types of dopamine receptors.