Evaluation of Aortic Elasticity Parameters in Survivors of COVID-19 Using Echocardiography Imaging.
Evaluation of Aortic Elasticity Parameters in Survivors of COVID-19 Using Echocardiography Imaging.
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DOI：
10.1159/000522626
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发表时间：
2022
影响因子：
3.2
通讯作者：
Aksit, Ercan
中科院分区：
文献类型：
--
作者：
Kucuk, Ugur;Gazi, Emine;Duygu, Ali;Aksit, Ercan
虽然严重急性呼吸综合征冠状病毒2（SARS-CoV-2）主要影响肺组织，但它可能对心血管系统造成直接或间接损害，并可能发生永久性损害。动脉僵硬度是心血管疾病风险的早期指标。本研究的目的是通过经胸超声心动图检查来确定SARS-CoV-2对血管系统的潜在影响。这项研究比较了COVID-19幸存者和没有COVID-19感染史的人之间的动脉僵硬度。使用超声心动图检查主动脉直径的差异。该研究包括50名在过去3-6个月内幸存的COVID-19患者和50名年龄和性别匹配的健康志愿者。在存活的COVID-19患者中，主动脉舒张期直径（厘米）（[3.1 ± 0.2] vs. [2.9 ± 0.1]，p < 0.001），脉压（PP）（[43.02 ± 14.05] vs. [35.74 ± 9.86]，p = 0.004），主动脉扩张性（[5.61 ± 3.57] vs. [8.31 ± 3.82]，p < 0.001），主动脉应变（[10.56 ± 4.91] vs. [13.88 ± 5.86]，p = 0.003），PP/每搏输出量指数（[1.25 ± 0.47] vs. [0.98 ± 0.28]，p = 0.001）和主动脉僵硬指数（[2.82 ± 0.47] vs. [2.46 ± 0.45]，p < 0.001）与对照组相比具有统计学显著性。与对照组相比，SARS-CoV-2可能导致COVID-19幸存者与动脉壁功能受损相关的主动脉弹性参数降低或受损。
While severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily affects lung tissue, it may cause direct or indirect damage to the cardiovascular system, and permanent damage may occur. Arterial stiffness is an early indicator of cardiovascular disease risk. The aim of our study was to establish the potential effects of SARS-CoV-2 on the vascular system evaluated by transthoracic echocardiographic examination. This study compared arterial stiffness between the survivors of COVID-19 and those without a history of COVID-19 infection. The difference in aortic diameter was examined using echocardiography. The study included 50 patients who survived COVID-19 in the last 3–6 months and 50 age- and gender-matched healthy volunteers. In surviving COVID-19 patients, aortic diastolic diameter in cm ([3.1 ± 0.2] vs. [2.9 ± 0.1], p < 0.001), pulse pressure (PP) ([43.02 ± 14.05] vs. [35.74 ± 9.86], p = 0.004), aortic distensibility ([5.61 ± 3.57] vs. [8.31 ± 3.82], p < 0.001), aortic strain ([10.56 ± 4.91] vs. [13.88 ± 5.86], p = 0.003), PP/stroke volume index ([1.25 ± 0.47] vs. [0.98 ± 0.28], p = 0.001), and aortic stiffness index ([2.82 ± 0.47] vs. [2.46 ± 0.45], p < 0.001) were statistically significant compared to the control group. SARS-CoV-2 may cause reduced or impaired aortic elasticity parameters linked to impaired arterial wall function in COVID-19 survivors compared with controls.
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影响因子：
1.7
作者：
Wasim D;Alme B;Jordal S;Lind Eagan TM;Tadic M;Mancia G;Guttormsen AB;Saeed S
通讯作者：
Saeed S
影响因子：
1.6
作者：
Cecelja M;Chowienczyk P
通讯作者：
Chowienczyk P
DOI：
10.1111/echo.14835
发表时间：
2020-09-19
影响因子：
1.5
作者：
Schott, Jason P.;Mertens, Amy N.;Abbas, Amr E.
通讯作者：
Abbas, Amr E.
影响因子：
18.2
作者：
Lambadiari, Vaia;Mitrakou, Asimina;Ikonomidis, Ignatios
通讯作者：
Ikonomidis, Ignatios
影响因子：
4.8
作者：
Pitsavos, C;Toutouzas, K;Toutouzas, P
通讯作者：
Toutouzas, P