A case of carcinoma of the lower lip with superior vena cava syndrome due to secondary mediastinal lymph node metastasis
A case of carcinoma of the lower lip with superior vena cava syndrome due to secondary mediastinal lymph node metastasis
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下唇癌继发纵隔淋巴结转移并发上腔静脉综合征1例
DOI：
10.5794/jjoms.55.585
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
I. Mataga
中科院分区：
文献类型：
--
作者：
H. Nanbu;A. Tanaka;Mie Tsujiuchi;Tohru Akashiba;H. Shinohara;I. Mataga
摘要我们报告一个下唇癌因纵膈淋巴结转移而造成上级腔静脉症候群的病例。病人是一位77岁的女性，被转介到我科治疗下唇右侧的肿瘤。组织学检查的活检标本显示分化良好的鳞状细胞癌。在全身麻醉下，以双侧颈淋巴结清扫术进行肿瘤整块切除。对切除标本的进一步组织学评价显示pN2c的诊断。六个月后，癌症在患者口腔的左角局部复发，手术切除了肿瘤。8个月后，左侧面部、颈部、前臂和手背突然出现水肿，并伴有头晕。患者胸部的计算机断层扫描显示左纵隔淋巴结转移，左颈内静脉、头臂静脉和呼吸道闭塞。静脉闭塞是由于转移性肿瘤压迫上级腔静脉所致。颈淋巴结清扫术后出现面部水肿时应考虑上腔静脉综合征。
: We report a case of carcinoma of the lower lip with superior vena cava syndrome（SVCS）due to secondary metastasis to the mediastinal lymph nodes. The patient, a 77 year-old woman, was referred to our department to treat a tumor in the right side of the lower lip. Histologic examination of a biopsy specimen revealed a well-differentiated squamouse cell carcinoma. The tumor was abraded by en bloc excision surgery with bilateral neck dissection under general anesthesia. Further histological evaluation of an excised specimen revealed a diag-nosis of pN2c. Six months later the cancer recurred locally in the left corner of the patient’smouth, and the tumor was removed surgically. Eight months later, edema suddenly developed on the left side of the face, neck, forearm, and back of hand, accompanied by dizziness. A computed tomographic scan of the patient’schest revealed metastasis to the left mediastinal lymph nodes, with occlusion of the left internal jugular vein, brachiocephalic veins, and respiratory tract. The occulded veins were attributed to compression of the superior vena cava by a metastatic tumor. SVCS should be considered whenever edema of the face appears after neck dissection.
口腔鳞状细胞癌侵袭和淋巴结转移模式的表达谱。
DOI：
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发表时间：
2007
期刊：
影响因子：
--
作者：
Kondoh N ;et. al.
通讯作者：
et. al.