Local circuitry in the anterior caudal lobe of the mormyrid cerebellum: a study of intracellular recording and labeling.
Local circuitry in the anterior caudal lobe of the mormyrid cerebellum: a study of intracellular recording and labeling.
复制标题
斑鸠小脑前尾叶的局部电路：细胞内记录和标记的研究。
DOI：
10.1002/cne.21682
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发表时间：
2008
期刊：
影响因子：
--
通讯作者：
Han,VictorZ
中科院分区：
文献类型：
--
作者：
Zhang,Yueping;Han,PhilF;Han,VictorZ
斑尾小脑的尾叶包括与侧线和第八神经感觉相关的前部和与电感觉相关的后部。本研究检查切片制剂中前部细胞的生理学和形态学。描述了浦肯野细胞的两种亚型：传出细胞和星状细胞。多极浦肯野细胞位于叶的中央区域，具有大的、多极的、多刺的树突和局部结束的轴突。小浦肯野细胞位于其前缘，与前粒状突起（EGa）相邻，分子区域有刺状树突。一些小浦肯野细胞的轴突局部终止，而其他此类细胞的轴突在切片表面被切割，表明它们突出到叶外。传出细胞也沿 EGa 边界分布。这些细胞在分子区域有薄而光滑的树突，它们的轴突在切片表面被切割。星状细胞具有薄而光滑的树突和局部终止的轴突。从生理学角度来看，所有类型的细胞都会对平行纤维激活做出反应，但只有多极浦肯野细胞表现出特征性的全或无攀爬纤维反应。尽管大多数浦肯野细胞在静息水平下发射单一类型的尖峰，但小浦肯野细胞的子集发射小而窄和大而宽的尖峰。因此，斑鸠小脑的前尾叶与哺乳动物小脑的不同之处在于具有不同亚型的浦肯野细胞和许多浦肯野细胞轴突的局部终止。 J.Comp。内罗尔。 509:1–22, 2008。© 2008 Wiley-Liss, Inc.
The caudal lobe of the mormyrid cerebellum includes the anterior portion, which is associated with the lateral line and eighth nerve senses, and the posterior portion, which is associated with the electrosense. This study examines the physiology and morphology of cells in the anterior portion in slice preparations. Two subtypes of Purkinje cells, efferent cells and stellate cells, are described. Multipolar Purkinje cells are located in the central region of the lobe, with large, multipolar, spiny dendrites and locally ending axons. Small Purkinje cells are located along its anterior border with the eminentia granularis anterior (EGa), with spiny dendrites in the molecular region. Axons of some small Purkinje cells end locally, whereas axons of other such cells are cut at the surface of the slices, suggesting that they project outside the lobe. Efferent cells are also distributed along the border with EGa. These cells have thin, smooth dendrites in the molecular region, and their axons are cut at the sliced surface. Stellate cells have thin, smooth dendrites and locally terminating axons. Physiologically, all types of cells respond to parallel fiber activation, but only multipolar Purkinje cells showed characteristic all‐or‐none climbing fiber responses. Although the majority of Purkinje cells fire a single type of spikes at resting level, a subset of small Purkinje cells fire small, narrow and large, broad spikes. Thus, the anterior caudal lobe of the mormyrid cerebellum is different from the mammalian cerebellum in having different subtypes of Purkinje cells and local termination of many Purkinje cell axons. J. Comp. Neurol. 509:1–22, 2008. © 2008 Wiley‐Liss, Inc.