Maternal and paternal history of myocardial infarction and risk of cardiovascular disease in men and women
Maternal and paternal history of myocardial infarction and risk of cardiovascular disease in men and women
复制标题
DOI：
10.1161/hc2901.093115
复制
发表时间：
2001-07-24
期刊：
影响因子：
37.8
通讯作者：
Buring, JE
中科院分区：
文献类型：
--
作者：
Sesso, HD;Lee, IM;Buring, JE
背景：很少有研究考察父亲和母亲心肌梗死史（包括心肌梗死年龄）对心血管疾病（CVD）风险的影响，特别是在女性中。方法和结果：我们前瞻性研究了来自医师健康研究的22071名男性和来自女性健康研究的39876名女性，包括父母史和心肌梗死年龄的数据。在男性中，2654例CVD病例发展超过13.0年；在女性中，563例CVD病例发生在6.2年以上。与没有父母病史的男性相比，只有母亲、只有父亲、母亲和父亲都有心肌梗死史的男性患心血管疾病的相对风险（RRs）分别为1.71、1.40和1.85；女性的rr分别为1:46、1.15和2.05。对于男性，产妇在MI时的年龄为
Background-Few studies have examined the effects of paternal and maternal history of myocardial infarction (MI), including age at MI, on cardiovascular disease (CVD) risk, particularly among women.Methods and Results-We prospectively studied 22071 men from the Physicians' Health Study and 39876 women from the Women's Health Study with data on parental history and age at MI. Among men, 2654 CVD cases developed over 13.0 years; among women, 563 CVD cases occurred over 6.2 years. Compared with men with no parental history, only maternal, only paternal, and both maternal and paternal history of MI conferred relative risks (RRs) of CVD of 1.71, 1.40, and 1.85; among women, the respective RRs were 1:46, 1.15, and 2.05. For men, maternal age at MI of