Acute disseminated encephalomyelitis due to abrus precatorius poisoning - A case report

Acute disseminated encephalomyelitis due to abrus precatorius poisoning - A case report
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DOI:
10.1016/j.jsps.2018.11.016
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发表时间:
2019-05-01
影响因子:
4.1
通讯作者:
James, Emmanuel
James, Emmanuel
中科院分区:
医学3区
文献类型:
--
作者:
Ninan, Elizabeth C.;James, Emmanuel

文献摘要

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Abrus precatorius,俗称‘Rosary pea’或‘Jequirity pea’,在中东被称为‘Shisham,Batrah-Hindi或Ain Alfreeth’,生长在世界热带和亚热带地区。这种植物的种子含有人类已知的最有效的毒素之一。用橡子种子中毒是一种罕见的情况,因为种子坚硬的外层通常会抵抗消化,这样的报告在文献中很少。我们在此介绍一位22岁的女士,由于故意咀嚼和吞咽牛至草籽,她在发病初期出现严重的呕吐、腹泻和马来石症,后来又出现癫痫发作和急性播散性脑脊髓炎。她在几个疗程的膜血浆置换和支持性护理下获救。血浆置换逆转了急性播散性脑脊髓炎的神经病理过程。(C)2019年提交人。爱思唯尔公司代表沙特国王大学制作和主办。
Abrus precatorius, commonly known as 'Rosary pea' or 'Jequirity pea' and known as 'Shisham, Batrah-Hindi or Ain Alfreeth' in the Middle East, grows wild in the tropical and subtropical areas of the world. The seeds of the plant contain one of the most potent toxins known to man. Poisoning with abrus seeds is a rare occurrence as the harder outer coat of the seeds generally resists digestion and such reports are scarce in the literature. We present here a case of a 22 year old lady who developed severe vomiting, diarrhoea and malena at the initial stages and later seizures and acute disseminated encephalomyelitis due to deliberate chewing and swallowing of abrus seeds. She was rescued with several sessions of membrane plasmapheresis and supportive care. The neuropathological process of acute disseminated encephalomyelitis due to abrus poisoning was reversed by plasmapheresis. (C) 2019 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University.