Push-Button Method To Create Nanopores Using a Tesla-Coil Lighter
Push-Button Method To Create Nanopores Using a Tesla-Coil Lighter
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DOI：
10.1021/acsomega.8b02660
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发表时间：
2019-01-01
期刊：
影响因子：
4.1
通讯作者：
Dwyer, Jason R.
中科院分区：
文献类型：
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作者：
Bandara, Y. M. Nuwan D. Y.;Karawdeniya, Buddini I.;Dwyer, Jason R.
浸入电解质溶液中的氮化硅薄膜的受控介电击穿（CDB）已被用于制造具有类似于10 nm和更小直径的单个纳米流体通道、纳米孔，其可用于单分子传感和离子电路构造。使用手持式Tesla线圈打火机通过类似于10 nm厚的氮化硅膜形成纳米流体离子导体。低开销Tesla线圈辅助方法（TCAM）需要对传统方法进行修改：通过包括水代替电解质和离散而不是连续电压应用来增加电路电阻。由此产生的离子电导可以与电压应用的数量调谐。TCAM和常规CDB产生具有不同电导率与pH曲线的纳米孔，表明不同的表面化学。尽管如此，使用典型测试分子，DNA的传感实验，产生的信号与通过其他方法制造的固态纳米孔的易位结果相当。因此，TCAM方法在其可以产生的纳米级离子导体的制造以及性质和功能方面提供了灵活性。
Controlled dielectric breakdown (CDB) of silicon nitride thin films immersed in electrolyte solution has been used to fabricate single nanofluidic channels with similar to 10 nm and smaller diameters, nanopores, useful in single-molecule sensing and ionic circuit construction. A hand-held Tesla-coil lighter was used to form nanofluidic ionic conductors through a similar to 10 nm thick silicon nitride membrane. Modifications to the conventional approach were required by the low-overhead Tesla-coil-assisted method (TCAM): increased circuit resistance by including water in place of electrolyte and discrete rather than continuous voltage applications. The resulting ionic conductance could be tuned with the number of voltage applications. TCAM and conventional CDB produced nanopores with different conductance versus pH curves, suggesting different surface chemistry. Nevertheless, sensing experiments using the canonical test molecule, lambda-DNA, produced signals comparable to translocation results through solid-state nanopores fabricated by other methods. Thus, the TCAM method offers flexibility in fabrication and in the properties and function of the nanoscale ionic conductors that it can generate.