MORPHOLOGIC HIPPOCAMPAL ASYMMETRY IN MALE AND FEMALE RATS

MORPHOLOGIC HIPPOCAMPAL ASYMMETRY IN MALE AND FEMALE RATS
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DOI:
10.1016/0014-4886(82)90124-8
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发表时间:
1982-01-01
影响因子:
5.3
通讯作者:
JOHNSON, RE
JOHNSON, RE
中科院分区:
医学2区
文献类型:
--
作者:
DIAMOND, MC;MURPHY, GM;JOHNSON, RE

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大鼠的海马结构在左右半球以及雄性和雌性中各不相同。对来自以下年龄的雄性Long-Evans大鼠的纤维素包埋的组织切片进行背侧海马厚度的形态学研究:6、10、14、26、41、55、77、90、108、185、300、400和650天。每个年龄组使用15 - 25只大鼠,共225只雄性大鼠。对47只90日龄雌性Long-Evans大鼠(11只正常,36只生后1天去卵巢)的卵巢进行了测量。在男性中,右侧海马体在某些年龄组(但不是所有年龄组)明显比左侧厚。在90日龄的雌性中,左侧海马比右侧厚。女性海马体中的这种左右模式并没有逆转,就像出生时卵巢切除后大脑皮层中的情况一样。
The hippocampus of the rat varies in structure in the right and left hemispheres and in males and females. A morphologic study of the thickness of the dorsal hippocampus was performed on celloidin-embedded histologic sections from male, Long-Evans rats of the following ages: 6, 10, 14, 26, 41, 55, 77, 90, 108, 185, 300, 400 and 650 days. Between 15 and 25 rats per age group were used, a total of 225 male rats. The hippocampi were measured on 47 Long-Evans female, 90-day-old rats: 11 normal and 36 animals ovariectomized 1 day after birth. In males, the right hippocampus was significantly thicker than the left for some but not all age groups. In the female at 90 days of age, the left hippocampus was thicker than the right. This left-right pattern in the female hippocampus did not reverse, as it did in the cerebral cortex after ovariectomy at birth.