Fat distribution in relation to age, degree of obesity, smoking habits, parity and estrogen use: a cross-sectional study in 11,825 Dutch women participating in the DOM-project.
Fat distribution in relation to age, degree of obesity, smoking habits, parity and estrogen use: a cross-sectional study in 11,825 Dutch women participating in the DOM-project.
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脂肪分布与年龄、肥胖程度、吸烟习惯、胎次和雌激素使用的关系：一项针对参与 DOM 项目的 11,825 名荷兰女性的横断面研究。
DOI：
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发表时间：
1990
影响因子：
4.9
通讯作者：
I. J. Ouwehand
中科院分区：
文献类型：
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作者：
I. Tonkelaar;J. Seidell;P. V. Noord;E. Halewijn;I. J. Ouwehand
在1984年至1986年期间，对11，825名40-73岁妇女的脂肪分布（腰/臀比）进行了评估，这些妇女接受了常规乳腺癌筛查（乌得勒支DOM项目）。腰臀比随克托莱指数和年龄的增加而增加。在调整克托莱指数和年龄后，绝经后妇女的腰臀比并不比绝经前妇女高。在绝经前和绝经后的妇女，腰/臀比增加，每天吸烟的数量增加（而克托莱指数下降）和一个积极的线性关系之间的奇偶校验和腰/臀比（也调整后的克托莱指数和年龄）。初潮年龄与克托莱指数呈显著负相关，但与腰臀比无关。在绝经后妇女中，报告使用雌激素治疗绝经期症状的妇女的腰/臀比低于未使用雌激素的类似妇女，但在调整年龄和肥胖程度后，这种差异消失。这项研究强调了一些与脂肪分布相关的变量的作用，这些变量是腹部肥胖风险估计的潜在混杂因素。
Fat distribution (waist/hip ratio) was assessed in a population of 11,825 women, aged 40-73 years, presenting for routine breast cancer screening (the DOM project in Utrecht) in the period 1984 to 1986. Waist/hip ratio increased with increasing Quetelet's index and age. Postmenopausal women did not have higher waist/hip ratios compared to premenopausal women after adjustment for Quetelet's index and age. In pre- and postmenopausal women, waist/hip ratio increased with increasing number of cigarettes smoked per day (while Quetelet's index decreased) and a positive linear relationship was found between parity and waist/hip ratio (also after adjustment for Quetelet's index and age). Age at menarche was strongly inversely related to Quetelet's index but was not related to waist/hip ratio. In postmenopausal women, waist/hip ratio was lower in women who reported to use oestrogens for menopausal complaints in comparison with similar women who did not, but this difference disappeared after adjustment for age and degree of obesity. This study emphasizes the role of some variables that are associated with fat distribution and are potential confounders of risk estimates of abdominal obesity.