A Quantitative and Radiomics approach to monitoring ARDS in COVID-19 patients based on chest CT: a cohort
A Quantitative and Radiomics approach to monitoring ARDS in COVID-19 patients based on chest CT: a cohort
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DOI：
10.7150/ijms.48432
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发表时间：
2020-01-01
影响因子：
3.6
通讯作者：
Song, Bin
中科院分区：
文献类型：
--
作者：
Chen, Yuntian;Wang, Yi;Song, Bin
基本原理：急性呼吸窘迫综合征（ARDS）是COVID-19患者进行通气和插管管理的主要原因之一，但目前尚无针对ARDS的无创成像监测方案。在这项研究中，我们的目的是开发一种基于传统的胸部CT定量和放射组学方法的无创性ARDS监测方案。方法：2020年1月20日至2020年3月31日诊断为COVID-19的患者入选本研究。从肺部感染区域的自动分割的感兴趣区域（ROI）中提取定量和放射组学数据。以Pa 02/Fi 02为指标评价ARDS的存在
Rationale: Acute respiratory distress syndrome (ARDS) is one of the major reasons for ventilation and intubation management of COVID-19 patients but there is no noninvasive imaging monitoring protocol for ARDS. In this study, we aimed to develop a noninvasive ARDS monitoring protocol based on traditional quantitative and radiomics approaches from chest CT.Methods: Patients diagnosed with COVID-19 from Jan 20, 2020 to Mar 31, 2020 were enrolled in this study. Quantitative and radiomics data were extracted from automatically segmented regions of interest (ROIs) of infection regions in the lungs. ARDS existence was measured by Pa02/Fi02