The Validity and Reliability of the Sinhala Translation of the Patient Health Questionnaire (PHQ-9) and PHQ-2 Screener.
The Validity and Reliability of the Sinhala Translation of the Patient Health Questionnaire (PHQ-9) and PHQ-2 Screener.
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DOI：
10.1155/2014/768978
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发表时间：
2014
影响因子：
--
通讯作者：
de Silva VA
中科院分区：
文献类型：
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作者：
Hanwella R;Ekanayake S;de Silva VA
患者健康调查问卷 (PHQ-9) 被改编并翻译成僧伽罗语。样本包括 75 名根据 DSM-IV 标准诊断为 MDD 的参与者和 75 名性别匹配的对照者。通过将 PHQ-9 总分与流行病学研究中心抑郁量表 (CESD) 的总分相关联来评估同时有效性。由精神科医生进行的 DSM-IV (SCID-II) 结构化临床访谈是黄金标准。样本的平均年龄为 33.0 岁。其中女性 91 人（60.7%）。病例 (14.71) 和对照 (2.55) 之间的平均 PHQ-9 评分存在显着差异 (P < 0.001)。分类算法的特异性为0.97；灵敏度为0.58。受试者工作特征 (ROC) 分析发现，截止分数≥10 的敏感性为 0.75，特异性为 0.97。曲线下面积（AOC）为0.93。两项筛选器 (PHQ-2) 的敏感性为 0.80，特异性为 0.97。 Cronbach 的 alpha 值为 0.90。 PHQ-9 是一种有效且可靠的工具，用于诊断非西方人群的 MDD。建议使用阈值算法而不是分类算法进行筛选。 PHQ-2筛查仪具有良好的灵敏度和特异性，推荐作为快速筛查仪器。
The Patient Health Questionnaire (PHQ-9) was adapted and translated into Sinhala. Sample consisted of 75 participants diagnosed with MDD according to DSM-IV criteria and 75 gender matched controls. Concurrent validity was assessed by correlating total score of PHQ-9 with that of Centre for Epidemiological Studies Depression Scale (CESD). The Structured Clinical Interview for DSM-IV (SCID-II) conducted by a psychiatrist was the gold standard. Mean age of the sample was 33.0 years. There were 91 females (60.7%). There was significant difference in the mean PHQ-9 scores between cases (14.71) and controls (2.55) (P < 0.001). The specificity of the categorical algorithm was 0.97; the sensitivity was 0.58. Receiver operating characteristic (ROC) analysis found that cut-off score of ≥10 had sensitivity of 0.75 and specificity of 0.97. The area under the curve (AOC) was 0.93. The sensitivity of the two-item screener (PHQ-2) was 0.80 and the specificity was 0.97. Cronbach's alpha was 0.90. The PHQ-9 is a valid and reliable instrument for diagnosing MDD in a non-Western population. The threshold algorithm is recommended for screening rather than the categorical algorithm. The PHQ-2 screener has good sensitivity and specificity and is recommended as a quick screening instrument.