Imaging characteristics of cardiac dominant diffuse large B-cell lymphoma demonstrated with MDCT and PET/CT
Imaging characteristics of cardiac dominant diffuse large B-cell lymphoma demonstrated with MDCT and PET/CT
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DOI：
10.1007/s00259-013-2436-5
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发表时间：
2013-09-01
影响因子：
9.1
通讯作者：
Shirato, Hiroki
中科院分区：
文献类型：
--
作者：
Kikuchi, Yasuka;Oyama-Manabe, Noriko;Shirato, Hiroki
为探讨心脏显性弥漫性大B细胞淋巴瘤（DLBCL）的多排螺旋CT（MDCT）和PET/CT（18）F-FDG）影像学表现，对5例DLBCL和12例其他心脏肿瘤（包括心包肿瘤）进行回顾性分析。在患有其他心脏肿瘤的患者中，7人患有转移性肿瘤，3人患有良性肿瘤，2人患有其他恶性心脏肿瘤。使用MDCT评估心脏肿块的位置、肿块包围的冠状动脉的包裹和心包积液。心脏肿瘤的疾病活动性也通过PET/CT进行了评价。5例DLBCL患者中有4例主要为右侧心脏病变，DLBCL中的这种病变比其他心脏肿瘤更常见（p = 0.028）。所有心脏DLBCL病变均位于房室沟周围并包裹冠状动脉。ECG门控心脏MDCT显示冠状动脉无明显狭窄。所有DLBCL患者均可见大量心包积液。PET/CT显示DLBCL的FDG摄取显著高于其他心脏恶性肿瘤，但无重叠（p = 0.0007）。MDCT显示右侧心脏肿块伴大量心包积液，包裹的冠状动脉无明显狭窄，高最大标准摄取值是心脏显性DLBCL的特异性结果。
To investigate the specific imaging findings of multidetector row CT (MDCT) and PET/CT with(18)F-FDG in cardiac dominant diffuse large B-cell lymphoma (DLBCL) in comparison with other cardiac tumours.Five patients with DLBCL and 12 patients with other cardiac tumours including pericardial tumours were retrospectively reviewed. Among the patients with other cardiac tumours, seven had metastatic tumours, three had benign tumours, and two had other malignant cardiac tumours. The location of the cardiac mass, the encasement of the coronary artery surrounded by the mass, and pericardial effusion were evaluated using MDCT. The disease activity of the cardiac tumour was also evaluated by PET/CT.Four of the five DLBCL patients had primarily right-sided cardiac lesions, which was seen significantly more frequently in DLBCL than in other cardiac tumours (p = 0.028). All cardiac DLBCL lesions were located around the atrioventricular groove and encased the coronary arteries. ECG-gated cardiac MDCT showed that there was no apparent stenosis of the coronary arteries. Large amounts of pericardial effusion were seen in all DLBCL patients. PET/CT revealed significantly higher FDG uptake in DLBCL than in other cardiac malignant tumours, with no overlap (p = 0.0007).The combination of a right-sided cardiac mass with a large pericardial effusion and no apparent stenosis of the encased coronary artery revealed by MDCT and a high maximum standard uptake value were the specific findings in cardiac dominant DLBCL.