The influence of the polyol solvents on the continuous growth of water-dispersible iron oxide nanoparticles
The influence of the polyol solvents on the continuous growth of water-dispersible iron oxide nanoparticles
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DOI：
10.1557/s43578-023-01236-x
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发表时间：
2023-12
影响因子：
2.7
通讯作者：
Jing Qu;Pohlee Cheah;Daniel Adams;Charles Collen;Yongfeng Zhao
中科院分区：
文献类型：
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作者：
Jing Qu;Pohlee Cheah;Daniel Adams;Charles Collen;Yongfeng Zhao
磁性纳米颗粒由于其独特的磁性和潜在的应用前景，继续受到人们的广泛关注。然而，直接合成尺寸可控的水分散磁性纳米粒子用于生物医学应用仍然具有挑战性。本研究考察了溶剂对磁性纳米粒子连续生长的影响，旨在通过在多元醇溶剂中的热分解来实现尺寸可控和良好的水分散性。随着多元醇链溶剂的增加，纳米粒子的尺寸逐渐增大。在较高的反应温度(220℃)比较低的反应温度(190℃)下，纳米颗粒尺寸的增大更为显著。这些单分散的纳米颗粒表现出很强的超顺磁性，在相同尺寸下，随着溶剂链的增加而改善。磁共振成像(MRI)研究表明，在较长链多元醇中合成的磁性纳米颗粒具有更高的弛豫性能。这项研究为合成具有精确尺寸、磁性和生物医学应用的磁性纳米颗粒提供了有价值的见解。图形摘要
Magnetic nanoparticles have continued to gain significant attention due to their unique magnetic properties and potential applications. However, it is still challenging to directly synthesize water-dispersible magnetic nanoparticles with controlled size for biomedical applications. This study investigates the influence of solvents on the continuous growth of magnetic nanoparticles, aiming to achieve controlled size and excellent water dispersibility via thermal decomposition in polyol solvents. The size of the nanoparticles gradually increases with longer polyol chain solvents. The increase in nanoparticles size is more significant under a higher reaction temperature (220 °C) compared to a lower temperature (190 °C). These monodispersed nanoparticles exhibit strong superparamagnetic properties, improving with longer solvent chain lengths at the same size. Magnetic resonance imaging (MRI) studies reveal higher relaxivities for magnetic nanoparticles synthesized in longer-chain polyols. This research offers valuable insights for synthesizing magnetic nanoparticles with precise sizes, magnetic properties, and biomedical applications. Graphical abstract