Association of self-reported alcohol use and hospitalization for an alcohol-related cause in Scotland: a record-linkage study of 23 183 individuals
Association of self-reported alcohol use and hospitalization for an alcohol-related cause in Scotland: a record-linkage study of 23 183 individuals
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DOI：
10.1111/j.1360-0443.2009.02497.x
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发表时间：
2009-04-01
期刊：
影响因子：
6
通讯作者：
Goldberg, David J.
中科院分区：
文献类型：
--
作者：
McDonald, Scott A.;Hutchinson, Sharon J.;Goldberg, David J.
调查苏格兰人口自我报告的饮酒水平与因酒精相关原因首次入院的关系。观察性记录关联研究。苏格兰，1995-2005 年。共有 23 183 名 16 岁及以上受访者参加了 1995 年、1998 年和 2003 年苏格兰健康调查，通过记录关联进行了从访谈日期到2005 年 9 月 30 日。至少诊断出与酒精相关的首次入院率。应用 Cox 比例风险回归分析来估计与日常饮酒水平相关的酒精相关疾病首次住院的相对风险（1-7、8-14、15-21、22-35、36-49、50+ 单位/周和戒酒者，与每周 < 1 单位相比）。在 SHS 参与者中，527 人在 135 313 期间因酒精相关原因住院。人年随访[每 10 000 人年中有 39 例首次入院，95% 置信区间 (CI) 36-42]。男性因酒精相关的住院率（61/10 000 人年，95% CI 54-67）明显高于女性（22/10 000 人年，95% CI 18-26）。与最低酒精消费类别（每周 < 1 单位）相比，首次因酒精相关入院的相对风险随着报告的饮酒量而增加：年龄调整后的风险比范围为 3 (1-5)（每周 1-7 单位）到 19 (10-37)（每周 50 单位以上）（男性）；每周 1-7 单位的 2 (1-3) 到每周 50 单位以上的 28 (14-56)（女性）。在调整了年龄和日常饮酒量后，对于报告酗酒的男性以及居住在最贫困地区的男性和女性来说，首次因酒精相关入院的相对风险仍然显着较高。中度和较高水平的日常饮酒和酗酒是苏格兰人口中因酒精相关住院的严重风险因素。这些发现有助于我们了解酒精摄入量与酒精相关发病率之间的关系。
To investigate the extent to which self-reported alcohol consumption level in the Scottish population is associated with first-time hospital admission for an alcohol-related cause.Observational record-linkage study.Scotland, 1995-2005.A total of 23 183 respondents aged 16 and over who participated in the 1995, 1998 and 2003 Scottish Health Surveys, followed-up via record-linkage from interview date until 30 September 2005.Rate of first-time hospital admission with at least one alcohol-related diagnosis. Cox proportional hazards regression analysis was applied to estimate the relative risk of first-time hospitalization with an alcohol-related condition associated with usual alcohol consumption level (1-7, 8-14, 15-21, 22-35, 36-49, 50+ units/week and ex-drinker, compared with < 1 unit per week).Of the SHS participants, 527 were hospitalized for an alcohol-related cause during 135 313 person-years of follow-up [39 first admissions per 10 000 person-years, 95% confidence interval (CI) 36-42]. Alcohol-related hospitalization rates were considerably higher for males (61/10 000 person-years, 95% CI 54-67) than for females (22/10 000 person-years, 95% CI 18-26). Compared with the lowest alcohol consumption category (< 1 unit per week), the relative risk of first-time alcohol-related admission increased with reported consumption: age-adjusted hazard ratios ranged from 3 (1-5) for 1-7 units/week to 19 (10-37) for 50+ units/week (males); and from 2 (1-3) for 1-7 units/week to 28 (14-56) for 50+ units/week (females). After adjusting for age and usual alcohol consumption, the relative risk of first-time alcohol-related admission remained significantly higher for males reporting binge drinking and for both males and females residing in the most deprived localities.Moderate and higher levels of usual alcohol consumption and binge drinking are serious risk factors for alcohol-related hospitalization in the Scottish population. These findings contribute to our understanding of the relationship between alcohol intake and alcohol-related morbidity.