Prostate Volume Growth Rate Changes over Time: Results from Men 18 to 92 Years Old in a Longitudinal Community-based Study
Prostate Volume Growth Rate Changes over Time: Results from Men 18 to 92 Years Old in a Longitudinal Community-based Study
复制标题
前列腺体积增长率随时间变化：基于社区的纵向研究中 18 至 92 岁男性的结果。
DOI：
10.1007/s11596-016-1664-x
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发表时间：
2016-12-01
影响因子：
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通讯作者：
Liu, Cheng-yun
中科院分区：
文献类型：
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作者：
Li, Si-hui;Yang, Qun-fang;Liu, Cheng-yun
先前的研究表明，老年男性的前列腺总体积（TPV）变化差异很大，相当一部分老年男性的前列腺大小保持稳定或缩小。尽管有大量文献描述了与良性前列腺增生相关的前列腺增大情况，但对于TPV增长率合适的年龄分界点却知之甚少。在这项基于社区的队列研究中，对连续进行健康检查的男性每年检查一次TPV，随访时间为4年。共纳入5058名男性（年龄18 - 92岁）。我们应用多元回归分析来评估TPV增长率与年龄之间的相关性。总体而言，在研究期间，3232名（63.9%）男性的前列腺出现增长，1826名（36.1%）男性的TPV保持稳定或缩小。TPV增长率与基线TPV呈负相关（r = -0.32，P （这里P值后面似乎缺失内容）
Previous investigations have shown that changes in total prostate volume (TPV) are highly variable among aging men, and a considerable proportion of aging men have a stable or decreasing prostate size. Although there is an abundance of literature describing prostatic enlargement in association with benign prostatic hyperplasia, less is known about the appropriate age cut-off points for TPV growth rate. In this community-based cohort study, TPV was examined once a year in men who had consecutive health checkup, during a follow-up of 4 years. A total of 5058 men (age 18-92 years old) were included. We applied multiple regression analyses to estimate the correlation between TPV growth rate and age. Overall, 3232 (63.9%) men had prostate growth, and 1826 (36.1%) had a stable or decreased TPV during the study period. The TPV growth rate was correlated negatively with baseline TPV (r=-0.32, P