Sensitivity of Birth Certificate Reports of Birth Defects in Atlanta, 1995-2005: Effects of Maternal, Infant, and Hospital Characteristics

Sensitivity of Birth Certificate Reports of Birth Defects in Atlanta, 1995-2005: Effects of Maternal, Infant, and Hospital Characteristics
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DOI:
10.1177/003335491112600209
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发表时间:
2011-03-01
影响因子:
3.3
通讯作者:
Correa, Adolfo
Correa, Adolfo
中科院分区:
医学4区
文献类型:
--
作者:
Boulet, Sheree L.;Shin, Mikyong;Correa, Adolfo

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目标.我们通过母亲、婴儿和医院特征评估了出生证明数据中出生缺陷诊断敏感性的变化。我们将1995-2005年亚特兰大出生的出生证明数据与亚特兰大大都会先天缺陷计划(MACDP)的数据进行了比较。我们计算了出生证明对报告出生时经常可辨别的缺陷的敏感性(例如,无脑畸形、脊柱裂、唇裂、马蹄内翻足、唐氏综合征和直肠闭锁或狭窄)。我们使用多变量逻辑回归模型来检验与社会人口统计学和医院因素的关联。出生证明的总体敏感性为23%,范围从直肠闭锁/狭窄的7%到无脑儿的69%。非西班牙裔黑人母亲的种族/民族,低于高中教育,早产独立与出生证明上报告的出生缺陷诊断的概率较低。对于每年出生人数超过1,000人的医院,敏感性也较低。出生证上出生缺陷的低报受社会人口和医院特征的影响。对出生证明报告中出生缺陷患病率估计值的解释应考虑到这些问题。
Objectives. We assessed variations in the sensitivity of birth defect diagnoses derived from birth certificate data by maternal, infant, and hospital characteristics.Methods. We compared birth certificate data for 1995-2005 births in Atlanta with data from the Metropolitan Atlanta Congenital Defects Program (MACDP). We calculated the sensitivity of birth certificates for reporting defects often discernable at birth (e.g., anencephaly, spina bifida, cleft lip, clubfoot, Down syndrome, and rectal atresia or stenosis). We used multivariable logistic regression models to examine associations with sociodemographic and hospital factors.Results. The overall sensitivity of birth certificates was 23% and ranged from 7% for rectal atresia/stenosis to 69% for anencephaly. Non-Hispanic black maternal race/ethnicity, less than a high school education, and preterm birth were independently associated with a lower probability of a birth defect diagnosis being reported on a birth certificate. Sensitivity also was lower for hospitals with > 1,000 births per year.Conclusions. The underreporting of birth defects on birth certificates is influenced by sociodemographic and hospital characteristics. Interpretation of birth defects prevalence estimates derived from birth certificate reports should take these issues into account.