Control of the Orientational Order and Nonlinear Optical Response of the "Push-Pull" Chromophore RuPZn via Specific Incorporation into Densely Packed Monolayer Ensembles of an Amphiphilic Four-Helix Bundle Peptide: Characterization of the Peptide-Chromophore Complexes
Control of the Orientational Order and Nonlinear Optical Response of the "Push-Pull" Chromophore RuPZn via Specific Incorporation into Densely Packed Monolayer Ensembles of an Amphiphilic Four-Helix Bundle Peptide: Characterization of the Peptide-Chromophore Complexes
复制标题
DOI：
10.1021/ja1010702
复制
发表时间：
2010-08-18
影响因子：
15
通讯作者：
Blasie, J. Kent
中科院分区：
文献类型：
--
作者：
Krishnan, Venkata;Tronin, Andrey;Blasie, J. Kent
基于扩展的π电子系统的“推拉”发色团已经被设计为表现出异常大的分子超极化率。我们已经设计了一种两亲性四螺旋束肽，以矢量方式将具有金属卟啉部分的这种超极化发色团以高特异性并入束的内部核心中。束的两亲性外部有利于在液-气界面处形成矢量取向的肽-发色团复合物的密集堆积的单层集合。设计到束的末端的化学特异性促进这些单层系综随后共价附着到无机基底的表面上。在这篇文章中，我们描述了这些单层合奏的结构表征，在每个阶段的制造一个这样的肽-发色团复合物指定为AP 0-RuPZn。在随附的文章中，我们描述了它们的宏观非线性光学性质的表征。
"Push-pull" chromophores based on extended pi-electron systems have been designed to exhibit exceptionally large molecular hyperpolarizabilities. We have engineered an amphiphilic four-helix bundle peptide to vectorially incorporate such hyperpolarizable chromophores having a metalloporphyrin moiety, with high specificity into the interior core of the bundle. The amphiphilic exterior of the bundle facilitates the formation of densely packed monolayer ensembles of the vectorially oriented peptide-chromophore complexes at the liquid-gas interface. Chemical specificity designed into the ends of the bundle facilitates the subsequent covalent attachment of these monolayer ensembles onto the surface of an inorganic substrate. In this article, we describe the structural characterization of these monolayer ensembles at each stage of their fabrication for one such peptide-chromophore complex designated as AP0-RuPZn. In the accompanying article, we describe the characterization of their macroscopic nonlinear optical properties.