Hybrid germanium/silica optical fibers for endoscopic delivery of erbium:YAG laser radiation.
Hybrid germanium/silica optical fibers for endoscopic delivery of erbium:YAG laser radiation.
复制标题
用于内窥镜传输铒：YAG 激光辐射的混合锗/石英光纤。
DOI：
10.1002/lsm.10249
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发表时间：
2004
期刊：
影响因子：
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通讯作者：
Fried,NathanielM
中科院分区：
文献类型：
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作者：
Chaney,CharlesA;Yang,Yubing;Fried,NathanielM
背景和目的由于缺乏坚固、灵活和生物相容的光纤传输系统，铒（Er）：YAG激光的内窥镜应用受到限制。本研究报告的混合锗/硅纤维能够提供Er：YAG激光辐射通过一个灵活的endoscience.Study设计/材料和MethodsHybrid光纤的测试组装从1厘米长，550 μm的核心，连接到350或425 μm的氧化锗“主干”光纤的硅纤维尖端。Er：YAG激光辐射（λ = 2.94 μm），激光脉冲长度为70和220微秒，脉冲重复率为3-10 Hz，激光输出能量高达300 mJ，通过光纤进行testing.ResultsMaximum光纤输出能量分别为180±30和82±20 mJ（n = 10），在光纤界面损伤发生之前，根据直和紧弯曲配置进行测量。相比之下，在接触软组织消融过程中，没有二氧化硅尖端的锗纤维的损伤阈值仅为9 mJ（n = 3）。使用混合纤维碎石术的研究也导致纤维损伤阈值（55-114毫焦耳）以上的石头消融阈值（15-23毫焦耳）。ConclusionsHybrid锗/硅纤维代表一个强大的，灵活的，和生物相容性的方法，提供Er：YAG激光辐射接触软组织消融。然而，显着的改进，在混合光纤将是必要的，然后才可以用于有效的Er：YAG激光碎石术。激光外科医学34：5-11，2004年。© 2004 Wiley利斯公司
Background and ObjectivesEndoscopic applications of the erbium (Er):YAG laser have been limited due to the lack of an optical fiber delivery system that is robust, flexible, and biocompatible. This study reports the testing of a hybrid germanium/silica fiber capable of delivering Er:YAG laser radiation through a flexible endoscope.Study Design/Materials and MethodsHybrid optical fibers were assembled from 1‐cm length, 550‐μm core, silica fiber tips attached to either 350‐ or 425‐μm germanium oxide “trunk” fibers. Er:YAG laser radiation (λ = 2.94 μm) with laser pulse lengths of 70 and 220 microseconds, pulse repetition rates of 3–10 Hz, and laser output energies of up to 300 mJ was delivered through the fibers for testing.ResultsMaximum fiber output energies measured 180±30 and 82±20 mJ (n = 10) under straight and tight bending configurations, respectively, before fiber interface damage occurred. By comparison, the damage threshold for the germanium fibers without silica tips during contact soft tissue ablation was only 9 mJ (n = 3). Studies using the hybrid fibers for lithotripsy also resulted in fiber damage thresholds (55–114 mJ) above the stone ablation threshold (15–23 mJ).ConclusionsHybrid germanium/silica fibers represent a robust, flexible, and biocompatible method of delivering Er:YAG laser radiation during contact soft tissue ablation. However, significant improvement in the hybrid fibers will be necessary before they can be used for efficient Er:YAG laser lithotripsy. Lasers Surg. Med. 34:5–11, 2004. © 2004 Wiley‐Liss, Inc.