THE GENOME OF PLASMODIUM-FALCIPARUM .1. DNA-BASE COMPOSITION
THE GENOME OF PLASMODIUM-FALCIPARUM .1. DNA-BASE COMPOSITION
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DOI：
10.1093/nar/10.2.539
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发表时间：
1982-01-01
影响因子：
14.9
通讯作者：
GOLENSER, J
中科院分区：
文献类型：
--
作者：
POLLACK, Y;KATZEN, AL;GOLENSER, J
本文用多种技术对恶性疟原虫DNA的某些结构特性进行了深入研究。它的G+C含量极低（17-19%），是生物体中最低的。DNA似乎仅由四种主要碱基组成，因为未检测到甲基化碱基。该DNA的Tm值为62.5°C，其变性曲线显示无明显的分子内异质性。
Some structural properties of the DNA ofPlasmodium falciparumwere studied thoroughly using several techniques. Its G+C content was found to be extremely low (17–19%), the lowest reported for a living organism. The DNA seems to be composed only of the four major bases as no methylated bases were detected. This DNA had a Tm value of 62.5°C and its denaturation profile showed no marked intramolecular heterogeneity.