Quantitative Analysis of the Effect of an Ectopic Beat on the Heart Rate Variability in the Resting Condition.
Quantitative Analysis of the Effect of an Ectopic Beat on the Heart Rate Variability in the Resting Condition.
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DOI：
10.3389/fphys.2018.00922
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发表时间：
2018
影响因子：
4
通讯作者：
Shin H
中科院分区：
文献类型：
--
作者：
Choi A;Shin H
本研究旨在从时域、频域和非线性分析中定量分析异位搏动对心率变异性（HRV）的影响。通过生成概率上包含漏拍或误检搏动的人工异位搏动来进行定量分析，并通过与无异位的HRV进行比较来评估统计学显著性，其中异位搏动的比率从0增加到50%，增量为0.1%。通过应用最近邻插值、线性插值和三次样条插值，研究了插值对异位HRV的影响。结果证实，即使在小于1%的异位HRV中，每个域的差异也具有统计学意义（P < 0.05）。当应用插值时，根据所使用的插值方法存在差异，但是对于异位搏动率从1 - 2%到几十个百分点，确保了统计学显著性。结果表明，线性插值和样条插值对心率变异性高频变量的影响较大，最近邻插值对心率变异性低频变量的影响较大。
The purpose of this study is to quantitatively analyze the effect of an ectopic beat on heart rate variability (HRV) in the time domain, frequency domain, and in a non-linear analysis. A quantitative analysis was carried out by generating artificial ectopic beats that probabilistically contained a missed beat or a false-detected beat, and the statistical significance was evaluated though a comparison with an ectopic-free HRV by increasing the ratio of the ectopic beat in 0.1% increments from 0 to 50%. The effect of the interpolation on the ectopic HRV was also investigated by applying nearest-neighbor interpolation, linear interpolation, and cubic spline interpolation. The results confirmed a statistically significant difference (P < 0.05) even in the less-than-1% ectopic HRV in every domain. When interpolation was applied, there were differences according to the interpolation method used, but statistical significance was secured for an ectopic beat ratio from 1 to 2% to several tens of a percent. In the effect, linear interpolation, and spline interpolation were confirmed to have a higher effect on the high-frequency related HRV variables, and nearest-neighbor interpolation had a higher effect on low-frequency related variables.
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