Association of whole-grain and dietary fiber intake with cardiometabolic risk in children and adolescents
Association of whole-grain and dietary fiber intake with cardiometabolic risk in children and adolescents
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DOI：
10.1177/0260106020928664
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发表时间：
2020-09-01
期刊：
影响因子：
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通讯作者：
Chu, YiFang
中科院分区：
文献类型：
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作者：
Fulgoni, Victor L., III;Brauchla, Mary;Chu, YiFang
背景：众所周知，饮食影响心血管疾病(CVD)的许多危险因素，心血管疾病是导致死亡和发病率的主要原因。目的：本研究的目的是利用2003-2014年的国家健康和营养检查调查(NHANES)，探讨全谷物和膳食纤维与儿童和青少年心血管疾病危险因素(包括代谢综合征)之间的潜在联系。方法：使用16507名2-18岁儿童和青少年的两天24小时回忆数据来估计膳食摄入量。通过聚合腰围、平均动脉压、高密度脂蛋白胆固醇、甘油三酯和血糖的年龄/性别回归z分数来计算连续蛋氨酸评分(CMetS)。在调整人口统计学因素后，使用回归分析评估纤维和全谷物摄入量与心脏代谢指标(包括蛋氨酸)的相关性。结果：在13-18岁的青少年中，纤维摄入量的增加与降低3%的危险蛋氨酸显著相关。此外，增加纤维摄入量与13-18岁青少年中胆固醇升高(5-11%)、舒张压升高(10%-23%)以及2-18岁儿童和青少年肥胖风险(3%-5%)的降低有关。在13-18岁的青少年中，增加全谷物摄入量只与降低甘油三酯升高的风险(风险降低52%)有关。结论：膳食纤维摄入量与包括蛋氨酸在内的心血管疾病风险的几个标志物呈负相关。
Background: Diet is known to affect many risk factors of cardiovascular disease (CVD), a leading cause of mortality and morbidity. Aim: The objective of this study was to explore the potential association between whole grain and dietary fiber with CVD risk factors, including metabolic syndrome (MetS) in children and adolescents using National Health and Nutrition Examination Survey (NHANES) 2003-2014. Methods: Two days of 24-hour recall data from 16,507 children and adolescents age 2-18 years were used to estimate dietary intakes. Continuous MetS scores (cMetS) were computed by aggregating age/sex regressed z-scores of waist circumference, mean arterial blood pressure, high-density lipoprotein-cholesterol, triglycerides, and glucose. Regression analyses were used to assess association of fiber and whole grain intake with cardiometabolic markers including MetS after adjusting for demographic factors. Results: Increasing tertiles of fiber intake were significantly associated with 3% lowered risk MetS in adolescents age 13-18 years. Additionally, increasing intake tertiles of fiber were associated with reduced risk elevated cholesterol (5-11% reduction), elevated diastolic blood pressure (10-23% reduction) in adolescents age 13-18 years, and risk of obesity (3-5% reduction) in children and adolescent age 2-18 years. Increasing tertiles of whole grain intake were only associated with reduced risk of elevated triglycerides (52% risk reduction) in adolescents age 13-18 years. Conclusion: The results suggest that intake of dietary fiber was inversely associated with several markers of cardiovascular disease risk including MetS.