Autogenous control of PspF, a constitutively active enhancer-binding protein of Escherichia coli
Autogenous control of PspF, a constitutively active enhancer-binding protein of Escherichia coli
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DOI：
10.1128/jb.179.16.5232-5237.1997
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发表时间：
1997-08-01
影响因子：
3.2
通讯作者：
Model, P
中科院分区：
文献类型：
--
作者：
Jovanovic, G;Dworkin, J;Model, P
大肠杆菌sigma（54）依赖性噬菌体休克蛋白操纵子（pspA to -E）的转录受组成活性激活剂PspF的控制，sigma（70）依赖性PspF的转录受野生型PspF的自生控制，而不受dna结合突变体PspF Delta HTH的控制。pspA的负自我调节是持续的，不受刺激的影响，如f1 pIV，诱导pspA到-E操纵子。PspF的产生独立于PspA （PspA到-E操纵子的负调节因子）和PspB和-C（正调节因子）。
Escherichia coli sigma(54)-dependent phage shock protein operon (pspA to -E) transcription is under the control of PspF, a constitutively active activator, sigma(70)-dependent transcription of pspF is under autogenous control by wild-type PspF but not by a DNA-binding mutant, PspF Delta HTH. Negative autoregulation of PspF is continual and not affected by stimuli, like f1 pIV, that induce the pspA to -E operon. PspF production is Independent of PspA (the negative regulator of the pspA to -E operon) and of PspB and -C (positive regulators).