Fast interactive CFD evaluation of hemodynamics assisted by RBF mesh morphing and reduced order models: the case of aTAA modelling
Fast interactive CFD evaluation of hemodynamics assisted by RBF mesh morphing and reduced order models: the case of aTAA modelling
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DOI：
10.1007/s12008-020-00694-5
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发表时间：
2020-09-10
影响因子：
2.1
通讯作者：
Celi, Simona
中科院分区：
文献类型：
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作者：
Biancolini, Marco Evangelos;Capellini, Katia;Celi, Simona
医疗数字孪生正在成为一个可行的机会，为治疗、预防和手术计划提供有用的患者特定信息。当采用计算流体动力学（CFD）技术和工具进行高保真血流预测时，其有效使用的瓶颈是需要大量的计算成本。减少订单模型（ROM）看起来是面对上述限制的一个有前途的解决方案。事实上，一旦ROM数据处理完成，消费阶段就可以在用于仿真的计算机辅助工程软件之外进行，此外，它还可以在医学环境中常用的交互式软件可视化界面上实现。在本文中，我们通过数值研究凸起形状对升胸主动脉动脉瘤病例的影响来证明这种概念的合理性。基于径向基函数（RBF）的网格变形可以实现参数化形状，用于构建ROM框架和数据。最终的结果是一个能够可视化、交互式和几乎实时的检测工具，形状参数对整个流场的影响。该方法首先通过考虑从普通健康患者到普通动脉瘤患者的变形行为进行验证(Capellini等人在欧洲生物力学学会意大利分会（ESB-ITA 2017）， 2017；Capellini et al. in J. Biomech。工程学报，140(11):111007-1-111007- 10,2018)。然后，定义并生成一组形状参数，这些参数适合于一致地表示大量可能的凸起配置。该概念考虑了收缩峰值条件下的稳定流场，分别使用ANSYS (R) Fluent (R)及其ROM环境进行CFD和ROM计算，并使用RBF Morph（TM）软件进行形状参数化。
The medical digital twin is emerging as a viable opportunity to provide patient-specific information useful for treatment, prevention and surgical planning. A bottleneck toward its effective use when computational fluid dynamics (CFD) techniques and tools are adopted for the high fidelity prediction of blood flow, is the significant computing cost required. Reduced order models (ROM) looks to be a promising solution for facing the aforementioned limit. In fact, once ROM data processing is accomplished, the consumption stage can be performed outside the computer-aided engineering software adopted for simulation and, in addition, it could be also implemented on interactive software visualization interfaces that are commonly employed in the medical context. In this paper we demonstrate the soundness of such a concept by numerically investigating the effect of the bulge shape for the ascending thoracic aorta aneurysm case. Radial basis functions (RBF) based mesh morphing enables the implementation of a parametric shape, which is used to build up the ROM framework and data. The final result is an inspection tool capable to visualize, interactively and almost in real-time, the effect of shape parameters on the entire flow field. The approach is first verified considering a morphing action representing the progression from an average healthy patient to an average aneurismatic one (Capellini et al. in Proceedings VII Meeting Italian Chapter of the European Society of Biomechanics (ESB-ITA 2017), 2017; Capellini et al. in J. Biomech. Eng. 140(11):111007-1-111007-10, 2018). Then, a set of shape parameters, suitable to consistently represent a widespread number of possible bulge configurations, are defined and accordingly generated. The concept is showcased taking into account the steady flow field at systolic peak conditions, using ANSYS (R) Fluent (R) and its ROM environment for CFD and ROM calculations respectively, and the RBF Morph(TM)software for shape parametrization.