Challenging Assumptions About Minority Participation in US Clinical Research
Challenging Assumptions About Minority Participation in US Clinical Research
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DOI：
10.2105/ajph.2011.300279
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发表时间：
2011-12-01
影响因子：
12.7
通讯作者：
Kalbaugh, Corey A.
中科院分区：
文献类型：
--
作者：
Fisher, Jill A.;Kalbaugh, Corey A.
尽管大量研究指出了少数群体参与临床研究的程度低的问题，但大多数研究几乎完全集中在治疗性试验上。现有文献可能掩盖了少数群体参与临床试验的重要问题，在需要健康志愿者参与的I期安全性研究中，少数民族实际上可能占了过多的比例。被剥夺公民权的群体;需要重新审查关于少数群体不信任、难以获得审判机会和其他参与审判障碍的文献。少数群体参与临床试验是公共卫生讨论中的一个重要议题，因为这种代表性涉及平等和消除不平等的问题，这是该领域的核心价值。(Am J公共卫生. 2011;101：2217-2222. doi：10.2105/AJPH.2011.300279）
Although extensive research addresses minorities' low participation in clinical research, most focuses almost exclusively on therapeutic trials.The existing literature might mask important issues concerning minorities' participation in clinical trials, and minorities might actually be overrepresented in phase I safety studies that require the participation of healthy volunteers.It is critical to consider the entire spectrum of clinical research when discussing the participation of disenfranchised groups; the literature on minorities' distrust, poor access, and other barriers to trial participation needs re-examination. Minority participation in clinical trials is an important topic in public health discussions because this representation touches on issues of equality and the elimination of disparities, which are core values of the field. (Am J Public Health. 2011;101: 2217-2222. doi:10.2105/AJPH.2011.300279)