Propindilactones E-J, schiartane nortriterpenoids from Schisandra propinqua var. propinqua

Propindilactones E-J, schiartane nortriterpenoids from Schisandra propinqua var. propinqua
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DOI:
10.1021/np8001699
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发表时间:
2008-07-01
影响因子:
5.1
通讯作者:
Sun, Han-Dong
Sun, Han-Dong
中科院分区:
生物学2区
文献类型:
--
作者:
Lei, Chun;Huang, Sheng-Xiong;Sun, Han-Dong

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Six new nortriterpenoids, propindilatones E-J (1-6), and two known (7, 8) schiartane-type nortriterpenoids were isolated from the stems of Schisandra propinqua var. propinqua. Their structures were elucidated by extensive spectroscopic analyses, and the structure of compound 4 was confirmed through single-crystal X-ray diffraction. The absolute configuration of compounds 1-3 was established using CD methods. Compounds 4-6 were noncytotoxic against K562, A549, and HT-29 human cancer cells.