Association of Visual Acuity and Cognitive Impairment in Older Individuals: Fujiwara-kyo Eye Study.
Association of Visual Acuity and Cognitive Impairment in Older Individuals: Fujiwara-kyo Eye Study.
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DOI：
10.1089/biores.2016.0023
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发表时间：
2016
影响因子：
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通讯作者：
Ogata N
中科院分区：
文献类型：
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作者：
Mine M;Miyata K;Morikawa M;Nishi T;Okamoto N;Kawasaki R;Yamashita H;Kurumatani N;Ogata N
视力障碍和认知障碍是决定老年人生活质量的重要因素。本研究的目的是确定在日本老年人群中视力和认知障碍之间是否存在相关性。Fujiwara-kyo眼科研究是一项在日本奈良县年龄≥ 68岁的受试者中开展的横断面研究。参与者接受眼科检查和认知功能测试。轻度视力损害定义为较好眼的最佳矫正视力（BCVA）> 0.2最小分辨角（logMAR）单位的对数。认知障碍定义为简易精神状态检查（MMSE）评分≤ 23分。共有2 818人完成了考试。参与者的平均年龄为76.3 ± 4.8岁（平均值±标准差）。较好眼的平均BCVA为− 0.02 ± 0.13 logMAR单位，6.6%的受试者被归类为轻度视力受损。平均MMSE评分为27.3 ± 2.3，5.7%的受试者被归类为认知受损。认知或中度视力障碍的受试者比例随着年龄的增长而增加，视力与MMSE评分之间存在显著相关性（r =-0.10，p <0.0001）。在调整年龄、性别和教育年限后，轻度视觉障碍受试者的认知障碍几率是无视觉障碍受试者的2.4倍（比值比2.4，95%置信区间，1.5 - 3.8，p <0.001）。我们的结论是，它可能是重要的，以保持良好的视力，以减少认知障碍的风险。
Both visual impairment and cognitive impairment are essential factors that determine the quality of life in the aged population. The aim of this study was to determine if a correlation existed between visual acuity and cognitive impairment in an elderly Japanese population. The Fujiwara-kyo Eye Study was a cross-sectional study of individuals aged ≥68 years who lived in Nara Prefecture of Japan. Participants underwent ophthalmological examinations and cognitive function test. A mild visual impairment was defined as having a best corrected visual acuity (BCVA) >0.2 logarithm of the minimum angle of resolution (logMAR) units in the better eye. Cognitive impairment was defined as having a Mini-Mental State Examination (MMSE) score of ≤23 points. A total to 2818 individuals completed the examinations. The mean age of the participants was 76.3 ± 4.8 years (mean ± standard deviation). The mean BCVA of the better eye was −0.02 ± 0.13 logMAR units and 6.6% subjects were classified as being mildly visually impaired. The mean MMSE score was 27.3 ± 2.3 and 5.7% subjects were classified as being cognitively impaired. The proportion of subjects with cognitive or moderate visual impairment increased with age, and there was a significant correlation between the visual acuity and MMSE score (r = −0.10, p < 0.0001). Subjects with mild visual impairments had 2.4 times higher odds of having cognitive impairment than those without visual impairment (odds ratio 2.4, 95% confidence interval, 1.5–3.8, p < 0.001) after adjusting for age, sex, and length of education. We conclude that it may be important to maintain good visual acuity to reduce the risk of having cognitive impairment.