THE STATIC ELASTIC PROPERTIES OF 45 HUMAN THORACIC AND 20 ABDOMINAL AORTAS INVITRO AND THE PARAMETERS OF A NEW MODEL
THE STATIC ELASTIC PROPERTIES OF 45 HUMAN THORACIC AND 20 ABDOMINAL AORTAS INVITRO AND THE PARAMETERS OF A NEW MODEL
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DOI：
10.1016/0021-9290(84)90034-4
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发表时间：
1984-01-01
影响因子：
2.4
通讯作者：
GOEDHARD, WJA
中科院分区：
文献类型：
--
作者：
LANGEWOUTERS, GJ;WESSELING, KH;GOEDHARD, WJA
尸检时，45条胸主动脉和20条腹主动脉(包括13对30-88岁的腹主动脉)的血流灌注为37度。C泰罗德‘’S溶液在原位长度。用平衡换能器测量了由20 mm Hg压力阶跃引起的直径变化，范围在20-180 mm Hg之间，精度为1微米。100毫米汞柱下的绝对直径测量精度为50微米。100 mm Hg时，胸段横截面积为2.6~7.6 cm~2，腹段横截面积为1.0~3.2 cm~2。胸部的依从性为1.9-17，依从性为0.6-4.4mm3/mm Hg.cntdo.厘米为腹部节段。具有3个自由参数的ArcTanGent模型A(P)=Am(1/2+tan-1((p-po)/p1).pi.)[式中Am为最大面积，p为跨壁压，po为最大顺应性/厘米压，pi为半宽压]可解释各主动脉面积随压力变化的99%以上。柔度、特性阻抗和传播速度的变化也同样得到了很好的描述。平均而言，腹痛的比例降低了2倍，从配对的胸部向更低的压力移动了20毫米汞柱(P=0.001)。
Segments of the 45 human thoracic and 20 abdominal aortas, including 13 pairs, aged 30-88 yr at autopsy, were perfused with 37.degree. C Tyrode''s solution at in-situ length. Diameter changes due to 20 mm Hg pressure steps, between 20-180 mm Hg, were measured to 1 .mu.m accuracy with balanced transducers. Absolute diameter at 100 mm Hg was measured to 50 .mu.m accuracy. At 100 mm Hg, cross-sectional area [A] ranged from 2.6-7.6 for thoracic and from 1.0-3.2 cm2 for abdominal segments. Compliances ranged from 1.9-17 for thoracic and from 0.6-4.4 mm3/mm Hg .cntdot. cm for abdominal segments. An arctangent model with 3 free parameters A(p) = Am (1/2 + tan-1 ((p-po)/p1).pi.) [where Am is the maximal area, p the transmural pressure, po the maximum aortic compliance/cm pressure and pi the half-width pressure] explained over 99% of the variance in area with pressure for each aorta. Changes in compliance, characteristic impedance and propagation velocity are equally well described. Abdominal fits on the average appeared down scaled by a factor of 2 and shifted 20 mm Hg towards lower pressures from paired thoracic (significant at P = 0.001).