Antioxidative and free radical scavenging activities of selected medicinal herbs

Antioxidative and free radical scavenging activities of selected medicinal herbs
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DOI:
10.1016/s0024-3205(99)00643-8
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发表时间:
2000-01-14
期刊:
影响因子:
6.1
通讯作者:
Ng, TB
Ng, TB
中科院分区:
医学2区
文献类型:
--
作者:
Liu, F;Ng, TB

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对12种中草药的抗氧化、清除超氧阴离子自由基和羟自由基以及促氧化作用进行了研究。黄连、牡丹、夏枯草和千里光水提物对大鼠红细胞溶血和肾、脑匀浆脂质过氧化的抑制作用最强。上述四种草药也表现出较强的清除超氧阴离子自由基和羟自由基的活性,但只产生轻微的促氧化作用。
The antioxidative and superoxide- and hydroxyl radical-scavenging activities and prooxidant effect of twelve selected medicinal herbs were studied. The aqueous extracts of Coptis chinensis, Paeonia suffruticosa, Prunella vulgaris and Senecio scandens exhibited the highest potency in inhibiting rat erythrocyte hemolysis and lipid peroxidation in rat kidney and brain homogenates. The aforementioned four herbs also demonstrated strong superoxide- and hydroxyl radical-scavenging activity, but exerted only a slight pro-oxidant effect.