Prevalence and determinants of pre-term deliveries in the University of Ilorin Teaching Hospital, Ilorin, Nigeria
Prevalence and determinants of pre-term deliveries in the University of Ilorin Teaching Hospital, Ilorin, Nigeria
复制标题
DOI：
10.4081/pr.2010.e3
复制
发表时间：
2010-01-01
影响因子：
1.1
通讯作者：
Adeniyi, A.
中科院分区：
文献类型：
--
作者：
Mokuolu, Olugbenga A.;Suleiman, B. M.;Adeniyi, A.
在尼日利亚，每年有超过90万名五岁以下儿童死亡。早产儿死亡占这些死亡病例的20%多一点。早产仍然是这些早产儿死亡的一个重要原因。在一些系列中，据报道，这些死亡中有60%-70%是由它造成的。这项研究旨在确定伊洛林大学教学医院早产的患病率和决定因素。这是一项在伊洛林大学教学医院进行的为期9个月的前瞻性队列研究。在此期间收集了分娩记录和关于产妇社会生物学和产前变量的数据，以确定早产的流行率和决定因素。在9个月内进行的2489次分娩中，有293次提前分娩，即每1000次分娩中有120次提前分娩。早产的重要影响因素是早产(P=0.001；OR=3.55；95%CI=1.71-7.3)，产前出血(P=0.000；OR=8.95；95%CI=4.06-19.78)，胎膜早破(P=0.000；OR=6.48；95%CI=4.33-9.67)，母体尿路感染(P=0.006；OR=5.89；95%CI=1.16~27.57)、妊娠高血压综合征(P=0.007；OR=3.23；95%CI=2.09~4.99)、劳动类型(P=0.000；OR=6.44；95%CI=4.429.38)和预订情况(P=0.000；OR=4.67；95%CI=3.33~6.56)。每1000名活产儿中就有120名早产。与早产显著相关的因素有社会经济地位低、既往早产、产前出血、胎膜早破、尿路感染、妊娠高血压综合征、引产、在教学医院以外的其他地方预定。
In Nigeria, over 900,000 children under the age of five years die every year. Early neonatal death is responsible for a little over 20% of these deaths. Prematurity remains a significant cause of these early neonatal deaths. In some series, it is reported to be responsible for 60-70% of these deaths. This study aimed to determine the prevalence and determinants of pre-term deliveries at the University of Ilorin Teaching Hospital, Ilorin. This was a prospective cohort study conducted over a 9-month period at the University of Ilorin Teaching Hospital. Records of deliveries and data on maternal socio-biological and antenatal variables were collected during this period in order to determine the prevalence and determinants of pre-term deliveries. Out of the 2,489 deliveries that took place over a 9-month period, there were 293 pre-terms, giving a pre-term delivery rate of 120 per 1,000 deliveries. Of the total deliveries, 1,522 singleton deliveries that satisfied inclusion criteria were recruited; 185 of them were pre-term deliveries giving a case:control ratio of 1:7. Significant determinants of pre-term delivery identified were previous pre-term delivery (P=0.001; OR=3.55; 95% CI=1.71-7.30), antepartum hemorrhage (P=0.000; OR=8.95; 95% CI=4.06-19.78), pre-mature rupture of the membranes (P=0.000; OR=6.48; 95% CI=4.33-9.67), maternal urinary tract infection (P=0.006; OR=5.89; 95% CI=1.16-27.57), pregnancy induced hypertension (P=0.007; OR=3.23; 95% CI=2.09-4.99), type of labor (P=0.000; OR=6.44; 95% CI=4.429.38) and booking status (P=0.000; OR=4.67; 95% CI=3.33-6.56). The prevalence of pre-term delivery was 120 per 1,000 live births. Factors significantly associated with pre-term delivery were low socio-economic class, previous pre-term delivery, antepartum hemorrhage, premature rupture of fetal membranes, urinary tract infection, pregnancy induced hypertension, induced labor, and booking elsewhere outside the teaching hospital.