Effective Intra-Arterial Chemotherapy for Acinar Cell Carcinoma of the Pancreas
Effective Intra-Arterial Chemotherapy for Acinar Cell Carcinoma of the Pancreas
复制标题
有效的动脉内化疗治疗胰腺腺泡细胞癌
作者：
T. Ukei;K. Okagawa;Y. Uemura;K. Miyauchi;T. Kaneko;S. Mizunoya;M. Monden
用5-氟尿嘧啶(5-FU)、丝裂霉素C(MMC)和顺铂(CDDP)对1例41岁胰腺巨大肿瘤(腺泡细胞癌)患者进行动脉插管化疗。肿瘤明显缩小，他接受了胰腺十二指肠切除术，并将肿瘤完全切除。不幸的是，切除后5个月发现了多发性转移性肝肿瘤。经动脉插管化疗后肿瘤体积明显缩小，生存期延长至18个月。他突然死于脓毒症，但不是死于胰腺癌。本病例表明5-FU、MMC、CDDP联合动脉插管化疗是治疗胰腺腺泡细胞癌的有效方案。
A 41-year-old man with a huge pancreatic tumor (acinar cell carcinoma) was treated by intra-arterial infusion chemotherapy with 5-fluorouracil (5-FU), mitomycin C (MMC) and cisplatin (CDDP). The tumor was significantly reduced, and he underwent a pancreaticoduodenectomy with complete excision of the tumor. Unfortunately multiple metastatic liver tumors were noted 5 months after resection. These tumors could also be markedly reduced by intra-arterial chemotherapy and the survival period was prolonged to 18 months. He suddenly died of sepsis but not from the pancreatic carcinoma. This case shows that intra-arterial infusion chemotherapy with 5-FU, MMC and CDDP can be an effective regimen for the treatment of acinar cell carcinoma of the pancreas.
5-氟尿嘧啶、阿霉素和顺铂联合治疗晚期上消化道腺癌的 II 期研究。
DOI：
10.1200/jco.1986.4.7.1053
发表时间：
1986
期刊：
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
影响因子：
--
作者：
Moertel,CG;Rubin,J;O'Connell,MJ;Schutt,AJ;Wieand,HS
通讯作者：
Wieand,HS