Total Small Vessel Disease Burden Predicts Functional Outcome in Patients With Acute Ischemic Stroke

Total Small Vessel Disease Burden Predicts Functional Outcome in Patients With Acute Ischemic Stroke
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总小血管疾病负担可预测急性缺血性中风患者的功能结果

DOI:
10.3389/fneur.2019.00808
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发表时间:
2019-08-06
影响因子:
3.4
通讯作者:
Qin, Xin-yue
Qin, Xin-yue
中科院分区:
医学3区
文献类型:
--
作者:
Huo, Ying-chao;Li, Qi;Qin, Xin-yue

文献摘要

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背景资料:脑小血管病(SVD)通常被认为是中风、残疾、步态障碍、血管性认知障碍和痴呆的原因。本研究的目的是调查总SVD负担是否可用于预测急性缺血性stroke.Methods功能结局:从2017年4月至2018年1月,对接受基线MRI扫描的急性缺血性卒中患者进行连续评估。在90天时使用改良兰金量表(mRS)评估功能结局,并定义为i)极好结局(mRS
Background: Cerebral small vessel disease (SVD) is generally considered as a cause of stroke, disability, gait disturbances, vascular cognitive impairment, and dementia. The aim of this study was to investigate whether the total SVD burden can be used to predict functional outcome in patients with acute ischemic stroke.Methods: From April 2017 to January 2018, consecutive patients with acute ischemic stroke who underwent baseline MRI scan were evaluated. The functional outcome was assessed using the modified Rankin Scale (mRS) at 90 days and defined as i) excellent outcome (mRS