Interstitial hyperthermia of experimental brain tumor using implant heating system
Interstitial hyperthermia of experimental brain tumor using implant heating system
复制标题
使用植入加热系统对实验性脑肿瘤进行间质热疗
DOI：
10.1007/bf00165105
复制
发表时间：
1989
影响因子：
3.9
通讯作者：
T. Ikeda
中科院分区：
文献类型：
--
作者：
Tatsuya Kobayashi;Takayuki Tanaka;Y. Kida;M. Matsui;T. Ikeda
本文介绍了一种新型低居里点铁磁性植入体脑肿瘤感应热疗实验系统。金属植入物为圆柱形针形，采用低居里点铁铂合金制成，适用于50~60℃的高温。研制了最大功率为200W、频率为100~500 kHz、磁功率为16.7Oe的感应线圈和发电机。单纯热疗(45℃，30min)可明显延长荷瘤小鼠的生存期和观察肿瘤的形态变化。
SummaryNew experimental system of induction hyperthermia for brain tumor using ferromagnetic implant with low Curie point has been developed. The metal implant is cylindrical needle and made of Fe-Pt alloy with low Curie point suitable for hyperthermia (50–60°C). Induction coil and generator which produce maximum power of 200 W and variable frequency of 100–500 kHz, yielding magnetic power of 16.7 Oe, have been developed.Interstitial hyperthermia was made on rat brain tumor model (T9 gliosarcoma) by this system. Significant effects of single hyperthermia (45°C for 30 minutes) were observed by the extension of life span and morphological changes of the tumor.