Why T waves change: a reminiscence and essay.

Why T waves change: a reminiscence and essay.
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DOI:
10.1016/j.hrthm.2009.07.022
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发表时间:
2009-11
期刊:
影响因子:
5.5
通讯作者:
Rosen, Michael R.
Rosen, Michael R.
中科院分区:
医学2区
文献类型:
--
作者:
Rosen, Michael R.

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下面的文章是我对一个长期以来一直感兴趣的课题的研究的个人反思,这个课题是T波,特别是作为心脏记忆标志的T波变化。我的兴趣是在毛里西奥·罗森鲍姆经常从布宜诺斯艾利斯到纽约旅行期间,我和他在阿尔冈琴酒店喝咖啡时发展起来的。阿尔冈琴有一些东西,其伤痕累累的木制桌面上有罗伯特·本奇利,多萝西帕克和20世纪20年代纽约文人的印记,还有一些关于Mauricio的东西-临床医生-科学家,朋友和非凡的健谈者-使他一再向我挑战“在你开始失去自己的记忆之前先看看心脏记忆”不可抗拒。于是,我开始了我个人的旅程,试图了解T波。我的路标是威尔逊和芬奇的实验,随后的一批调查人员的敏锐观察,以及毛里西奥的偶像崇拜见解。故事还远没有结束……我怀疑我在有生之年看不到它的结局。但如果发现之美在于航行,那么对我来说,这是一次难忘的旅行。
The following article is a personal reflection on my study of a subject which has long interested me. The subject is the T wave, and especially the T wave changes occurring as a marker of cardiac memory. My interest evolved over coffees that Mauricio Rosenbaum and I used to share at the Hotel Algonquin during his frequent trips from Buenos Aires to New York. There is something about the Algonquin, whose scarred wooden tabletops carry the imprints of Robert Benchley, Dorothy Parker, and the 1920's New York literati, and there was something about Mauricio—clinician-scientist, friend, and raconteur extraordinaire—that made his repeated challenges to me to “look at cardiac memory before you begin losing your own” irresistible. So began my personal voyage into trying to understand the T wave. My guideposts were the experiments of Wilson and Finch,1the astute observations of a host of investigators who followed, and Mauricio's iconoclastic insights. The story is far from over…I doubt I'll see the end of it in my lifetime. But if the beauty of discovery is in the voyage, then it has been – for me - a memorable trip.
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