The Association between Gray Matter Volume and Reading Proficiency: A Longitudinal Study of Beginning Readers
The Association between Gray Matter Volume and Reading Proficiency: A Longitudinal Study of Beginning Readers
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DOI：
10.1162/jocn_a_00710
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发表时间：
2015-02-01
影响因子：
3.2
通讯作者：
Lonnemann, Jan
中科院分区：
文献类型：
--
作者：
Linkersdoerfer, Janosch;Jurcoane, Alina;Lonnemann, Jan
大量功能成像研究已经确定了参与书面语言处理的神经系统。然而，在识字习得过程中发生的皮质解剖结构变化在很大程度上仍然未知。在这里，我们跟踪小学生前两年的正式阅读教学，并使用基于张量的形态测量将阅读能力与基线和后续测量的皮层体积以及两个测量时间点之间的个体内纵向体积发展联系起来。研究发现，左侧颞上回的基线灰质体积与随后的阅读能力变化之间存在正相关关系。此外，第二个测量时间点的阅读能力与个体内顶下小叶以及左半球中央前回和中央后回的皮质体积发育之间存在负相关关系。这些结果被解释为证据，表明阅读习得与预先存在的结构差异以及涉及树突和突触修剪的经验依赖性结构变化有关。
Neural systems involved in the processing of written language have been identified by a number of functional imaging studies. Structural changes in cortical anatomy that occur in the course of literacy acquisition, however, remain largely unknown. Here, we follow elementary school children over their first 2 years of formal reading instruction and use tensor-based morphometry to relate reading proficiency to cortical volume at baseline and follow-up measurement as well as to intraindividual longitudinal volume development between the two measurement time points. A positive relationship was found between baseline gray matter volume in the left superior temporal gyrus and subsequent changes in reading proficiency. Furthermore, a negative relationship was found between reading proficiency at the second measurement time point and intraindividual cortical volume development in the inferior parietal lobule and the precentral and postcentral gyri of the left hemisphere. These results are interpreted as evidence that reading acquisition is associated with preexisting structural differences as well as with experience-dependent structural changes involving dendritic and synaptic pruning.